Evidence map›Paper›PMID 37171127›Full record

ArticleThyroid : official journal of the American Thyroid Association2023

The Tyrosine Kinase Inhibitor Lenvatinib Inhibits Anaplastic Thyroid Carcinoma Growth by Targeting Pericytes in the Tumor Microenvironment.

Asumi Iesato, Stephanie Li, Peter M Sadow, Mohammadreza Abbasian, Ara Nazarian, Jack Lawler, Carmelo Nucera

Open access · greenAbstract read
In one paragraph

Article in Thyroid : official journal of the American Thyroid Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Asumi IesatoHuman Thyroid Cancers Preclinical and Translational Research Program, Division of Experimental Pathology, Cancer Research Institute (CRI), Cancer Center, Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Stephanie LiHuman Thyroid Cancers Preclinical and Translational Research Program, Division of Experimental Pathology, Cancer Research Institute (CRI), Cancer Center, Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Peter M SadowDepartment of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0003-1036-6367
Mohammadreza AbbasianMusculoskeletal Translational Innovation Initiative, Department of Orthopedic Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Ara NazarianMusculoskeletal Translational Innovation Initiative, Department of Orthopedic Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Jack LawlerCenter for Vascular Biology Research (CVBR), Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Carmelo NuceraHuman Thyroid Cancers Preclinical and Translational Research Program, Division of Experimental Pathology, Cancer Research Institute (CRI), Cancer Center, Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Beth Israel Deaconess Medical Center · USBroad Institute · USHarvard University · US

Funding

Role of newly identified, thyroid-specific LincRNA in BRAFV600E thyroid carcinomaR01CA248031 · NCI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI NUCERA, CARMELO · 2020 to 2024
$2.0M
NCI NIH HHS R01 CA248031
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Thyroid Carcinoma, AnaplasticThyroid NeoplasmsAnimalsDisease Models, AnimalHumansIodine RadioisotopesMicePericytesPhenylurea CompoundsProtein Kinase InhibitorsProto-Oncogene Proteins B-rafQuinolinesThrombospondin 1Tumor MicroenvironmentTyrosine Kinase InhibitorsIodine RadioisotopeslenvatinibPhenylurea CompoundsProtein Kinase InhibitorsProto-Oncogene Proteins B-rafQuinolinesThrombospondin 1Tyrosine Kinase Inhibitorsanaplastic thyroid cancerBRAFV600ElenvatinibPDGFR-βpericyte

Identifiers

PMID37171127
PMCPMC10354711
OpenAlexW4376225907

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.