Evidence map›Paper›PMID 37170636›Full record

ArticleJournal of child psychology and psychiatry, and allied disciplines2023

Categorical and dimensional approaches to the developmental relationship between ADHD and irritability.

Rania Johns-Mead, Nandita Vijayakumar, Melissa Mulraney, Glenn Melvin, George Youssef, Emma Sciberras, Vicki A Anderson, Jan M Nicholson, Daryl Efron, Philip Hazel and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of child psychology and psychiatry, and allied disciplines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Rania Johns-MeadCentre for Social and Early Emotional Development (SEED) and School of Psychology, Deakin University, Geelong, Vic., Australia.
Nandita VijayakumarCentre for Social and Early Emotional Development (SEED) and School of Psychology, Deakin University, Geelong, Vic., Australia.
Melissa MulraneyInstitute for Social Neuroscience, ISN Psychology, Ivanhoe, Vic., Australia.ORCID 0000-0003-1953-6481
Glenn MelvinCentre for Social and Early Emotional Development (SEED) and School of Psychology, Deakin University, Geelong, Vic., Australia.
George YoussefCentre for Social and Early Emotional Development (SEED) and School of Psychology, Deakin University, Geelong, Vic., Australia.
Emma SciberrasCentre for Social and Early Emotional Development (SEED) and School of Psychology, Deakin University, Geelong, Vic., Australia.ORCID 0000-0003-2812-303X
Vicki A AndersonMurdoch Children's Research Institute, Melbourne, Vic., Australia.
Jan M NicholsonJudith Lumley Centre, La Trobe University, Melbourne, Vic., Australia.
Daryl EfronMurdoch Children's Research Institute, Melbourne, Vic., Australia.
Philip HazelSydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.
Tim J SilkCentre for Social and Early Emotional Development (SEED) and School of Psychology, Deakin University, Geelong, Vic., Australia.
Deakin University · AURoyal Children's Hospital · AUIvanhoe Energy (Canada) · CALa Trobe University · AUThe University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAttention deficit hyperactivity disorder (ADHD) and irritability commonly co-occur, and follow similar developmental trajectories from childhood to adolescence. Understanding of the developmental relationship between these co-occurrences is limited. This study provides a longitudinal assessment of how ADHD diagnostic status and symptom patterns predict change in irritability.

methodsA community sample of 337 participants (45.2% ADHD), recruited for the Childhood Attention Project, completed the Affective Reactivity Index (ARI) to measure irritability at baseline (mean age 10.5 years) and follow-up after 18-months. Latent change score models were used to assess how (a) baseline ADHD vs. control group status, (b) baseline symptom domain (inattention, hyperactivity-impulsivity) and (c) longitudinal change in ADHD symptom severity predicted change in irritability.

resultsIrritability was significantly higher among the ADHD group than controls; however, change in irritability over time did not differ between groups. When assessed across the entire cohort, change in irritability was predicted by higher symptom count in the hyperactive-impulsive domain, but not the inattentive domain. Greater declines in ADHD symptoms over time significantly predicted greater declines in irritability. Baseline ADHD symptom severity was found to significantly predict change in irritability; however, baseline irritability did not significantly predict change in ADHD symptoms.

conclusionsADHD symptoms-particularly hyperactive-impulsive symptoms-predict the degree and trajectory of irritability during childhood and adolescence, even when symptoms are below diagnostic thresholds. The use of longitudinal, dimensional and symptom domain-specific measures provides additional insight into this relationship.

Indexed as

Attention Deficit Disorder with HyperactivityAdolescentChildCognitionHumansImpulsive BehaviorIrritable MoodADHDirritabilitylatent change scorelongitudinal

Identifiers

PMID37170636
PMCPMC10952727
OpenAlexW4376226286

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.