Evidence map›Paper›PMID 37170188›Full record

ArticleBMC bioinformatics2023

A neural network model to screen feature genes for pancreatic cancer.

Jing Huang, Yuting Zhou, Haoran Zhang, Yiming Wu

Abstract read
In one paragraph

Article in BMC bioinformatics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jing Huang *Department of Gastroenterology, First Hospital of Jiaxing, Jiaxing, 314001, Zhejiang, China.
Yuting Zhou *Department of Respiratory, The 904Th Hospital of Joint Logistic Support Force of PLA, Affiliated Hospital of Jiangnan University, Wuxi, 214000, Jiangsu, China.
Haoran ZhangDepartment of Gastroenterology, First Hospital of Jiaxing, Jiaxing, 314001, Zhejiang, China.
Yiming WuDepartment of Gastroenterology, First Hospital of Jiaxing, Jiaxing, 314001, Zhejiang, China. jxyywxb@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

All the time, pancreatic cancer is a problem worldwide because of its high degree of malignancy and increased mortality. Neural network model analysis is an efficient and accurate machine learning method that can quickly and accurately predict disease feature genes. The aim of our research was to build a neural network model that would help screen out feature genes for pancreatic cancer diagnosis and prediction of prognosis. Our study confirmed that the neural network model is a reliable way to predict feature genes of pancreatic cancer, and immune cells infiltrating play an essential role in the development of pancreatic cancer, especially neutrophils. ANO1, AHNAK2, and ADAM9 were eventually identified as feature genes of pancreatic cancer, helping to diagnose and predict prognosis. Neural network model analysis provides us with a new idea for finding new intervention targets for pancreatic cancer.

Indexed as

Pancreatic NeoplasmsADAM ProteinsHumansMachine LearningMembrane ProteinsNeural Networks, ComputerADAM9 protein, humanADAM ProteinsMembrane ProteinsBiomarkersGene expression profilingNeural network modelPancreatic cancerRandom forest

Identifiers

PMID37170188
PMCPMC10176951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.