Evidence map›Paper›PMID 37170159›Full record

ArticleTrials2023

Effects of programmed flexor-extensor alternating electrical acupoint stimulation on upper limb motor functional reconstruction after stroke: study protocol for a double-blind, randomized controlled trial.

Yang Liu, Xu Dong, Hong Huo, Liyuan Feng, Dan Tong, Jiahui Liu, Hongyan Zhang, Yingkang Zheng, Shuai Wang, Dongyan Wang

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05333497 (Study on the Effect Mechanism of Programmed Flexor-extensor Alternating Electrical Acupiont Stimulation on Upper Limb Functional Reconstruction After Stroke), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05333497 nacompletednot on this map

Study on the Effect Mechanism of Programmed Flexor-extensor Alternating Electrical Acupiont Stimulation on Upper Limb Functional Reconstruction After Stroke: Study Protocol for a Randomized Controlled Trail

TypeinterventionalSponsorYang LiuRan2022 to 2023Enrolled84ConditionsStroke Sequelae, Movement DisordersArmsthe fourth programmed generation of low-frequency acupoint electric stimulation therapy instrument, the fourth generation of low-frequency acupoint electric stimulation therapy instrument
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Yang LiuHeilongjiang University of Chinese Medicine, No. 24 Heping Road, Xiangfang District, Harbin, People's Republic of China.
Xu DongThe Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Nangang District, No. 105 AshiheRoad, Harbin, People's Republic of China.
Hong HuoThe Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Nangang District, No. 105 AshiheRoad, Harbin, People's Republic of China.
Liyuan FengThe Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Nangang District, No. 105 AshiheRoad, Harbin, People's Republic of China.
Dan TongHeilongjiang University of Chinese Medicine, No. 24 Heping Road, Xiangfang District, Harbin, People's Republic of China.
Jiahui LiuHeilongjiang University of Chinese Medicine, No. 24 Heping Road, Xiangfang District, Harbin, People's Republic of China.
Hongyan ZhangHeilongjiang University of Chinese Medicine, No. 24 Heping Road, Xiangfang District, Harbin, People's Republic of China.
Yingkang ZhengHeilongjiang University of Chinese Medicine, No. 24 Heping Road, Xiangfang District, Harbin, People's Republic of China.
Shuai WangHeilongjiang University of Chinese Medicine, No. 24 Heping Road, Xiangfang District, Harbin, People's Republic of China.
Dongyan WangHeilongjiang University of Chinese Medicine, No. 24 Heping Road, Xiangfang District, Harbin, People's Republic of China. Docwdy@126.com.
Heilongjiang University of Chinese Medicine · CN

Funding

Natural Science Foundation of Heilongjiang Province LH2019H113
6 · The paper itself

Abstract

backgroundStroke's prevalence and morbidity are increasing (Guano, et al. Neuro 89:53-61, 2017), and limb motor dysfunction is left in most patients (Gittler, et al. JAMA 319:820-821, 2018). Particularly, the rehabilitation of upper limbs is more difficult and time-consuming (Borges, et al. The Cochrane database of systematic reviews 10:CD011887, 2018).

methodsA double-blind randomized controlled trial (RCT) will be conducted to investigate whether a new functional electrical stimulation (FES) combined with acupoint therapy is more effective in the rehabilitation of upper limb motor dysfunction after stroke. Patients who meet the inclusion criteria will be randomly divided into two groups: programmed flexor-extensor alternating electrical acupoint stimulation group (PES group) and conventional flexor-extensor alternating electrical acupoint stimulation group (CES group), which will be treated for 3 weeks. The primary outcome measures are electroencephalogram (EEG) and surface electromyogram (sEMG). The secondary outcome variables include MBI (modified Barthel index), China Stroke Scale (CSS), FMA-U (Fugl-Meyer assessment upper limb), MMT (manual muscle testing), and Brunnstrom. DISCUSSION: The results of this study are expected to verify the efficacy of PES therapy in the rehabilitation of upper limb motor function after stroke. This may promote the widespread use of the therapy in hospitals, communities, and homes for early and continuous treatment.

trial registrationClinicalTrials.gov NCT05333497. Registered on April 11, 2022.

Indexed as

Musculoskeletal DiseasesStrokeStroke RehabilitationAcupuncture PointsElectric StimulationHumansRandomized Controlled Trials as TopicRecovery of FunctionSystematic Reviews as TopicTreatment OutcomeUpper ExtremityAcupointElectrical stimulationFlexor–extensorProgrammedStroke sequelaeUpper limb motor dysfunction

Identifiers

PMID37170159
PMCPMC10174617
OpenAlexW4376128587

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.