Evidence map›Paper›PMID 37170003›Full record

Trial reportLangenbeck's archives of surgery2023

Chronic pain following totally extra-peritoneal inguinal hernia repair: a randomized clinical trial comparing glue and absorbable tackers.

Igor Jeroukhimov, Daniel Dykman, Yehuda Hershkovitz, Natan Poluksht, Vladimir Nesterenko, Amir Ben Yehuda, Albert Stephansky, Oded Zmora

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Langenbeck's archives of surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Igor Jeroukhimov *Department of Surgery, Shamir Medical Center, Beer Yaakov, affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel. igorjer65@gmail.com.
Daniel Dykman *Department of Surgery, Shamir Medical Center, Beer Yaakov, affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Yehuda HershkovitzDepartment of Surgery, Shamir Medical Center, Beer Yaakov, affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Natan PolukshtDepartment of Surgery, Shamir Medical Center, Beer Yaakov, affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Vladimir NesterenkoDepartment of Surgery, Shamir Medical Center, Beer Yaakov, affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Amir Ben YehudaDepartment of Surgery, Shamir Medical Center, Beer Yaakov, affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Albert StephanskyDepartment of Surgery, Shamir Medical Center, Beer Yaakov, affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Oded ZmoraDepartment of Surgery, Shamir Medical Center, Beer Yaakov, affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeChronic pain following inguinal hernia repair occurs in up to 20% of patients. The underlying mechanism probably involves sensory nerve damage and abnormal healing that might be influenced by the materials chosen for mesh fixation. The main objective of this study was to compare glue and absorbable tackers on the rate of chronic pain after surgery in patients undergoing totally extraperitoneal inguinal hernia repair (TEP).

methodsPatients undergoing (TEP) inguinal hernia repair were enrolled in a single-blind randomized clinical trial and were randomized for mesh fixation with glue (LIQUIBAND FIX 8 Neopharm) or absorbable tackers (SECURE STRAP Johnson & Johnson). Pain was assessed using a validated 4-point verbal-rank scale (none, mild, moderate, and severe) at 1 week, 1 month, 6 months, and 1 year postoperatively. Chronic pain was defined as pain persisting beyond 3 months.

resultsTwo hundred and eight patients were analyzed. The groups were similar in age, gender, and hernia side. Chronic pain of any intensity was reported in 31.7% (66/208) after 6 months and in 13% (29/208) after 12 months. No differences in postoperative pain were observed between the two forms of mesh fixation. Still, when only those with severe pain were considered, mesh fixation with glue resulted in less pain compared to fixation by tackers (log-rank p = 0.025). At 1 year, 4 symptomatic recurrent hernias were identified in patients whose mesh was fixated with absorbable tackers.

conclusionsPatients who underwent TEP inguinal hernia repair with mesh fixated by glue suffered from less pain.

Indexed as

Chronic PainHernia, InguinalLaparoscopyHerniorrhaphyHumansPeritoneumPostoperative PainRecurrenceSingle-Blind MethodSurgical MeshTreatment OutcomeChronic painEndoscopic hernia repairInguinal hernia

Identifiers

PMID37170003
PMCPMC10174730

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.