Evidence map›Paper›PMID 37169780›Full record

ArticleTranslational psychiatry2023

Association between brain serotonin 4 receptor binding and reactivity to emotional faces in depressed and healthy individuals.

Anjali Sankar, Brice Ozenne, Vibeke H Dam, Claus Svarer, Martin B Jørgensen, Kamilla W Miskowiak, Vibe G Frokjaer, Gitte M Knudsen, Patrick M Fisher

Open access · goldAbstract read
In one paragraph

Article in Translational psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Chronic, combinatorial targeting of NMDARs and 5-HTNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025
    Article
  3. PET-MRI Applications and Future Prospects in Psychiatry.Journal of magnetic resonance imaging : JMRI · 2025
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Anjali SankarNeurobiology Research Unit, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Brice OzenneNeurobiology Research Unit, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Vibeke H DamNeurobiology Research Unit, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Claus SvarerNeurobiology Research Unit, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0001-7811-1825
Martin B JørgensenDepartment of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-1321-8901
Kamilla W MiskowiakNeurocognition and Emotion in Affective Disorders (NEAD) Centre, Mental Health Services, Capital Region of Denmark, and Department of Psychology, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-2572-1384
Vibe G FrokjaerNeurobiology Research Unit, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Gitte M KnudsenNeurobiology Research Unit, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0003-1508-6866
Patrick M FisherNeurobiology Research Unit, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark. patrick@nru.dk.ORCID 0000-0002-8115-0611
University of Copenhagen · DKCopenhagen University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain serotonergic (5-HT) signaling is posited to modulate neural responses to emotional stimuli. Dysfunction in 5-HT signaling is implicated in major depressive disorder (MDD), a disorder associated with significant disturbances in emotion processing. In MDD, recent evidence points to altered 5-HT

Indexed as

Major Depressive DisorderBrainEmotionsHumansMagnetic Resonance ImagingReceptors, Serotonin, 5-HT4SerotoninReceptors, Serotonin, 5-HT4Serotonin

Identifiers

PMID37169780
PMCPMC10175268
OpenAlexW4376128552

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.