Evidence map›Paper›PMID 37169644›Full record

ArticleAnais brasileiros de dermatologia

Chemotherapeutical treatment of basal cell carcinoma with bleomycin via microinfusion of the drug into the skin (MMP®).

Paulo Rodrigo Pacola, Renato Roberto Liberato Rostey, Fernanda de Figueiredo Arruda Rizzo

Open access · goldAbstract read
In one paragraph

Article in Anais brasileiros de dermatologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Paulo Rodrigo PacolaDepartment of Dermatology, Hospital Universitário Júlio Muller, Cuiabá, MT, Brazil. Electronic address: paulopacola@bol.com.br.
Renato Roberto Liberato RosteyDepartment of Dermatology, Hospital Universitário Júlio Muller, Cuiabá, MT, Brazil.
Fernanda de Figueiredo Arruda RizzoDepartment of Dermatology, Hospital Universitário Júlio Muller, Cuiabá, MT, Brazil.
Hospital Universitário de Brasília · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBleomycin is a chemotherapeutical drug used to treat several neoplasias, including non-melanoma skin cancer; it is effective in the treatment of basal cell carcinoma (BCC) via intralesional infiltration. Transdermal drug delivery, which includes technologies such as CO

objectiveTo treat BCC lesions using bleomycin via MMP®.

methodsNinety-eight BCC lesions in different anatomical areas were treated using MMP® technology to administer and uniformly distribute bleomycin throughout the lesion and in the established safety margin.

resultsThe cure rate after six months was 96.94%; and recurrences were not associated with lesion size and/or depth. Adverse effects were the expected ones. STUDY LIMITATIONS: The follow-up time was only six months.

conclusionThis therapeutic route showed to be promising and effective.

Indexed as

Basal Cell CarcinomaSkin NeoplasmsAdministration, CutaneousBleomycinHumansPharmaceutical PreparationsBleomycinPharmaceutical PreparationsBleomycinCarcinoma, basal cellDrug therapySkin neoplasmsTherapeutics

Identifiers

PMID37169644
PMCPMC10404503
OpenAlexW4376224086

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.