Evidence map›Paper›PMID 37169498›Full record

ArticleBMJ open2023

Exploration of the Acceptance of the Use of Procalcitonin Point-of-Care Testing and Lung Ultrasonography by General Practitioners to Decide on Antibiotic Prescriptions for Lower Respiratory Infections: A Qualitative Study.

Daniel Geis, Nina Canova, Loïc Lhopitallier, Andreas Kronenberg, Jean-Yves Meuwly, Nicolas Senn, Yolanda Mueller, Fabienne Fasseur, Noémie Boillat-Blanco

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03191071 (Procalcitonin and Lung Ultrasonography Point-of-care Testing to Decide on Antibiotic Prescription in Patients With Lower Respiratory Tract Infection at Primary Care Level), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03191071 nacompletednot on this map

Procalcitonin and Lung Ultrasonography Point-of-care Testing to Decide on Antibiotic Prescription in Patients With Lower Respiratory Tract Infection at Primary Care Level: Pragmatic Cluster Randomized Trial

TypeinterventionalSponsorCentre Hospitalier Universitaire VaudoisRan2018 to 2020Enrolled469ConditionsLower Resp Tract InfectionArmsUltraPro, Procalcitonin, Blood sampling, Naso-pharyngeal swab and sputum culture
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Daniel GeisResearch Center for Psychology of Health, Aging and Sport Examination (PHASE), University of Lausanne, Lausanne, Switzerland.
Nina CanovaResearch Center for Psychology of Health, Aging and Sport Examination (PHASE), University of Lausanne, Lausanne, Switzerland canovanina7@gmail.com.ORCID 0000-0002-7407-4577
Loïc LhopitallierInfectious Diseases Service, Lausanne University Hospital, Lausanne, Switzerland.
Andreas KronenbergInstitute for Infectious Diseases, University of Bern, Bern, Switzerland.
Jean-Yves MeuwlyDepartment of Radiology, Lausanne University Hospital, Lausanne, Switzerland.
Nicolas SennDepartment of Family Medicine, Center for Primary Care and Public Health, Lausanne, Switzerland.
Yolanda MuellerDepartment of Family Medicine, Center for Primary Care and Public Health, Lausanne, Switzerland.
Fabienne FasseurResearch Center for Psychology of Health, Aging and Sport Examination (PHASE), University of Lausanne, Lausanne, Switzerland.
Noémie Boillat-BlancoInfectious Diseases Service, Lausanne University Hospital, Lausanne, Switzerland.
University of Lausanne · CHUniversity of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWe aimed to explore the acceptance and opinions of general practitioners (GPs) on the use of procalcitonin point-of-care and lung ultrasonography for managing patients with lower respiratory tract infections in primary care. We suppose that there are several factors that can influence the physician's antibiotic prescribing decision, and the implementation of a new tool will only be possible when it can be inserted into the physician's daily practice, helping him/her in the decision-making process.

designSemistructured interviews; data analysis using the grounded theory method.

settingLausanne, Switzerland.

participants12 GPs who participated in the randomised clinical trial UltraPro, which evaluated the impact of the use of procalcitonin only or an algorithm combining procalcitonin and lung ultrasonography on antibiotic prescription.

resultsGPs had mostly positive attitudes towards the use of point-of-care procalcitonin in lower respiratory tract infections and uncertainties regarding the usefulness of ultrasonography. Physicians' prescribing decisions result from interactions between three kinds of TrustS (core category): 'self-confidence', 'trust in the results' and 'trust in the doctor-patient relationship'. Procalcitonin reinforced the three levels of trust, while ultrasonography only strengthened the physician-patient relationship. To facilitate implementation of procalcitonin, physicians pointed out the need of coverage by insurance and of clear guidelines describing the targeted patient population.

conclusionsOur data show that there is a preference for the implementation of procalcitonin rather than lung ultrasonography for the management of patients with lower respiratory tract infections in primary care. Coverage by insurance plans and updated guidelines are prerequisite to the successful implementation of procalcitonin testing in primary care. TRIAL REGISTRATION NUMBER: NCT03191071.

Indexed as

General PractitionersRespiratory Tract InfectionsAnti-Bacterial AgentsFemaleHumansLungMalePhysician-Patient RelationsPoint-of-Care TestingPractice Patterns, Physicians'ProcalcitoninUltrasonographyAnti-Bacterial AgentsProcalcitoninClinical trialsGENERAL MEDICINE (see Internal Medicine)QUALITATIVE RESEARCHRespiratory infectionsRESPIRATORY MEDICINE (see Thoracic Medicine)Ultrasound

Identifiers

PMID37169498
PMCPMC10186440
OpenAlexW4376226405

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.