Evidence map›Paper›PMID 37169397›Full record

ArticleBMJ health & care informatics2023

Prevalence of electronic screening for sepsis in National Health Service acute hospitals in England.

Kate Honeyford, Amen-Patrick Nwosu, Runa Lazzarino, Anne Kinderlerer, John Welch, Andrew J Brent, Graham Cooke, Peter Ghazal, Shashank Patil, DiAlS Co-investigators and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMJ health & care informatics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Glucans: A Therapeutic Alternative for Sepsis Treatment.Journal of immunology research · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Kate HoneyfordTeam Health Informatics, Institute of Cancer Research, London, UK kate.honeyford@icr.ac.uk.ORCID http://orcid.org/0000-0002-5533-7693
Amen-Patrick NwosuMRC Centre for Global Infectious Disease Analysis, Jameel Institute, School of Public Health, Imperial College London, London, UK.ORCID http://orcid.org/0000-0001-6991-7798
Runa LazzarinoNuffield Department of Primary Care and Health Sciences, University of Oxford, Oxford, UK.
Anne KinderlererImperial College Healthcare NHS Trust, London, UK.
John WelchCritical Care Department, University College Hospital, London, UK.
Andrew J BrentOxford University Hospitals NHS Foundation Trust, Oxford, UK.
Graham CookeImperial College Healthcare NHS Trust, London, UK.
Peter GhazalSystems Immunity Research Institute, School of Medicine, Cardiff University, Cardiff, UK.
Shashank PatilEmergency Department, Chelsea and Westminster Healthcare NHS Trust, London, UK.
DiAlS Co-investigators
Ceire E CostelloeTeam Health Informatics, Institute of Cancer Research, London, UK.
Imperial College Healthcare NHS Trust · GBRoyal Marsden NHS Foundation Trust · GBUniversity of Oxford · GBCardiff University · GBImperial College London · GBInstitute of Cancer Research · GBUniversity College Hospital · GB

Funding

Medical Research Council MR/R015600/1
6 · The paper itself

Abstract

Sepsis is a worldwide public health problem. Rapid identification is associated with improved patient outcomes-if followed by timely appropriate treatment.

objectivesDescribe digital sepsis alerts (DSAs) in use in English National Health Service (NHS) acute hospitals.

methodsA Freedom of Information request surveyed acute NHS Trusts on their adoption of electronic patient records (EPRs) and DSAs.

resultsOf the 99 Trusts that responded, 84 had an EPR. Over 20 different EPR system providers were identified as operational in England. The most common providers were Cerner (21%). System C, Dedalus and Allscripts Sunrise were also relatively common (13%, 10% and 7%, respectively). 70% of NHS Trusts with an EPR responded that they had a DSA; most of these use the National Early Warning Score (NEWS2). There was evidence that the EPR provider was related to the DSA algorithm. We found no evidence that Trusts were using EPRs to introduce data driven algorithms or DSAs able to include, for example, pre-existing conditions that may be known to increase risk.Not all Trusts were willing or able to provide details of their EPR or the underlying algorithm. DISCUSSION: The majority of NHS Trusts use an EPR of some kind; many use a NEWS2-based DSA in keeping with national guidelines.

conclusionMany English NHS Trusts use DSAs; even those using similar triggers vary and many recreate paper systems. Despite the proliferation of machine learning algorithms being developed to support early detection of sepsis, there is little evidence that these are being used to improve personalised sepsis detection.

Indexed as

SepsisState MedicineEnglandHospitalsHumansPrevalencedecision support systems, clinicaldelivery of health careelectronic health recordsmedical records systems, computerized

Identifiers

PMID37169397
PMCPMC10186434
OpenAlexW4376225655

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.