Evidence map›Paper›PMID 37169005›Full record

ReviewInternational journal of particle therapy2023

Proton Beam Radiation Therapy for Oropharyngeal Squamous Cell Carcinoma.

William M Mendenhall, Jonathan J Beitler, Nabil F Saba, Ashok R Shaha, Sandra Nuyts, Primož Strojan, Heleen Bollen, Oded Cohen, Robert Smee, Sweet Ping Ng and 4 more

Open access · diamondAbstract readReview
In one paragraph

Review in International journal of particle therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 12 institutions in 6 countries.

William M MendenhallDepartment of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USA.
Jonathan J BeitlerHarold Alfonds Center for Cancer Care, Maine General Hospital, Augusta, ME, USA.
Nabil F SabaDepartment of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, USA.
Ashok R ShahaDepartment of Head and Neck Surgery and Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Sandra NuytsDepartment of Radiation Oncology, Leuven Cancer Institute, University Hospitals Leuven, KU Leuven - University of Leuven, Leuven, Belgium.
Primož StrojanDepartment of Radiation Oncology, Institute of Oncology, Ljubljana, Slovenia.
Heleen BollenDepartment of Radiation Oncology, Leuven Cancer Institute, University Hospitals Leuven, KU Leuven - University of Leuven, Leuven, Belgium.
Oded CohenDepartment of Otolaryngology - Head and Neck Surgery and Oncology, Soroka Medical Center, Tel Aviv, Affiliated with Ben Gurion University of the Negev, Beer Sheva, Israel.
Robert SmeeDepartment of Radiation Oncology, The Prince of Wales Cancer Centre, Sydney, NSW, Australia.
Sweet Ping NgDepartment of Radiation Oncology, Olivia Newton-John Cancer Centre, Austin Health, Melbourne, Australia.
Avraham EisbruchDepartment of Radiation Oncology, University of Michigan Medicine, Ann Arbor, Michigan, USA.
Wai Tong NgDepartment of Clinical Oncology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Jessica M KirwanDepartment of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USA.
Alfio FerlitoCoordinator of the International Head and Neck Scientific Group, Padua, Italy.
KU Leuven · BEBen-Gurion University of the Negev · ILConsumers for Affordable Health Care · USEmory University · USFlorida College · USInstitute of Oncology Ljubljana · SIMemorial Sloan Kettering Cancer Center · USMichigan Medicine · USOlivia Newton-John Cancer Wellness & Research Centre · AUPrince of Wales Hospital · AUUniversity of Florida · USUniversity of Hong Kong · HK

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Purpose: To discuss the role of proton beam therapy (PBT) in the treatment of patients with oropharyngeal squamous cell carcinoma (OPSCC). Materials and Methods: A review of the pertinent literature. Results: Proton beam therapy likely results in reduced acute and late toxicity as compared with intensity-modulated radiation therapy (IMRT). The extent of the reduced toxicity, which may be modest, depends on the endpoint and technical factors such as pencil beam versus passive scattered PBT and adaptive replanning. The disease control rates after PBT are likely similar to those after IMRT. Conclusion: Proton beam therapy is an attractive option to treat patients with OPSCC. Whether it becomes widely available depends on access.

Indexed as

cancer outcomeshead and neck canceroropharynxparticle therapy

Identifiers

PMID37169005
PMCPMC10166016
OpenAlexW4372057199

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.