Evidence map›Paper›PMID 37168995›Full record

ReviewFrontiers in pharmacology2023

Emerging role of ferroptosis-related circular RNA in tumor metastasis.

Yifei Meng, Jingdong Cao, Yidan Li, Saili Duan, Zongjiang Zhou, Jinghe Li, Diabate Ousmane, Chunlin Ou, Junpu Wang

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yifei MengDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, China.
Jingdong CaoDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, China.
Yidan LiDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, China.
Saili DuanDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, China.
Zongjiang ZhouDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, China.
Jinghe LiDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, China.
Diabate OusmaneDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, China.
Chunlin OuDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, China.
Junpu WangDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, China.
Xiangya Hospital Central South University · CNCentral South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor metastasis is an important factor that contributes to the poor prognosis of patients with tumors. Therefore, to solve this problem, research on the mechanism of metastasis is essential. Ferroptosis, a new mode of cell death, is characterized by membrane damage due to lipid peroxidation caused by iron overload. Many studies have shown that excessive ferroptosis can affect tumor metastasis and thus inhibit tumor progression. Recently, circular RNA (circRNA), a type of non-coding RNA, has been shown to be associated with the progression of ferroptosis, thus influencing tumor development. However, the specific mechanisms by which circRNAs affect the progression of ferroptosis and their roles in tumor metastasis are not known. In this review, we systematically discuss the role of circRNAs in regulating tumor ferroptosis and their mechanism of action through sponging miRNAS in various tumors, thereby impacting metastasis. This review helps elucidate the relationship and role of ferroptosis-related circRNAs in tumor metastasis and may provide future researchers with new ideas and directions for targeted therapies.

Indexed as

biomarkersCircRNAsferroptosistherapeutic targettumor metastasis

Identifiers

PMID37168995
PMCPMC10164976
OpenAlexW4366828144

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.