Evidence map›Paper›PMID 37168980›Full record

ReviewFrontiers in endocrinology2023

Research progress of E3 ubiquitin ligase regulating biological behavior of human placental trophoblast cells.

Jun Feng, Huimei Yin, Baturuhu, Yonghui Dai, Fuxiao Dai, Junjun Xu, Zhili Chen, Yanyan Liu

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Regulation of placental development and function by ubiquitination.Molecular medicine (Cambridge, Mass.) · 2025
    Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jun FengDepartment of Emergency Medicine, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China.
Huimei YinDepartment of Emergency Medicine, People's Hospital of Bortala Mongol Autonomous Prefecture, Bole, China.
BaturuhuDepartment of Neurosurgery Intensive Care Unit (ICU), People's Hospital of Bortala Mongol Autonomous Prefecture, Bole, China.
Yonghui DaiObstetrics Department, People's Hospital of Bortala Mongol Autonomous Prefecture, Bole, China.
Fuxiao DaiObstetrics Department, People's Hospital of Bortala Mongol Autonomous Prefecture, Bole, China.
Junjun XuObstetrics Department, People's Hospital of Bortala Mongol Autonomous Prefecture, Bole, China.
Zhili ChenObstetrics Department, People's Hospital of Bortala Mongol Autonomous Prefecture, Bole, China.
Yanyan LiuObstetrics and Gynecology Department, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China.
Tongji Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

E3 ubiquitin ligases are important components of the ubiquitin protease system. This family includes many proteins, which can catalyze the ubiquitination of a variety of protein substrates and promote the degradation of them by the proteasome system. Recent studies have shown that E3 ubiquitin ligase plays a key role in the process of fetal development and placental formation. It affects the biological behavior of placental trophoblast cells, leading to a series of pregnancy complications that threaten mothers and babies greatly. This review focuses on the regulation, target and mechanism of E3 ubiquitin ligase on the biological behavior of human placental trophoblast cells.

Indexed as

TrophoblastsUbiquitin-Protein LigasesFemaleHumansPlacentaPregnancyUbiquitinUbiquitinationUbiquitinUbiquitin-Protein LigasesapoptosisE3 ubiquitin ligasehuman trophoblast cellsinvasivenessin vitro migrationpregnancy complicationsproliferation and differentiation

Identifiers

PMID37168980
PMCPMC10165996
OpenAlexW4365515695

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.