ReviewCancer diagnosis & prognosis
Spindle Cell Lipoma and Pleomorphic Lipoma: An Update and Review.
Review in Cancer diagnosis & prognosis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 26 citations in OpenAlex.
- Fat-Containing Soft Tissue Lesions of the Limbs and Body Wall-A Pictorial Essay.Journal of medical imaging and radiation oncology · 2026Review
- A Challenging Case of Pleomorphic Lipoma of the Shoulder Mimicking Liposarcoma.The American journal of case reports · 2026Article
- Myxoid spindle cell lipoma of the ileum: Clinicopathological features and diagnostic insights.CytoJournal · 2026Article
- Spindle cell lipoma of the forehead overlying the supraorbital nerve associated with chronic cluster-like headaches: a case report.International journal of women's dermatology · 2025Article
- Indeterminate Subcutaneous Lesion of the Nasal Dorsum in an Adolescent: A Multidisciplinary Approach to a Rare Case of Spindle Cell Lipoma.Dermatopathology (Basel, Switzerland) · 2025Article
- The Enigmatic Mass Over the Clavicle: A Case Report Unveiling a Rapidly Growing Spindle Cell Lipoma.Cureus · 2025Article
- A case report unveiling spindle cell lipoma.Radiology case reports · 2025Article
- An asymptomatic flesh-colored tumor on the dorsal hand.JAAD case reports · 2025Article
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- Myxolipoma of the Popliteal Fossa: A Rare Tumor Case Report.Reports (MDPI) · 2024Article
- Giant pleomorphic lipoma in patient with multiple osteochondromatosis.Journal of surgical case reports · 2024Article
- Recent Advances in the Diagnosis, Pathogenesis, and Management of Myxoinflammatory Fibroblastic Sarcoma.International journal of molecular sciences · 2024Review
- Case report: Para-testicular spindle cell lipoma suspected of well-differentiated liposarcoma.Frontiers in urology · 2024Article
- "Low-fat" intradermal spindle cell lipoma of the upper eyelid: a case report.Digital journal of ophthalmology : DJO · 2024Article
- Myxoid Pleomorphic Liposarcoma: A Review and Update.Cancer genomics & proteomicsReview
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spindle cell lipoma (SCL) is a benign adipocytic tumor that primarily occurs in the subcutis of the posterior neck, upper back, and shoulder, particularly of middle-aged males. SCL and pleomorphic lipoma (PL) represent a morphological spectrum of one disease process. The lesion typically presents as a relatively small (<5 cm), mobile, slow-growing, painless mass. Magnetic resonance imaging reveals the lesion to be a well-defined subcutaneous mass with a mixture of adipose and non-adipose components. Intense enhancement of the non-adipose component is seen after contrast administration. Histologically, SCL is composed of variable distributions of mature adipocytes, bland spindle cells and ropey collagen bundles and PL also contains pleomorphic and multinucleated floret-like giant cells. By immunohistochemistry, the spindle and pleomorphic/floret-like giant cells of SCL/PL are diffusely positive for CD34 and show loss of nuclear RB transcriptional corepressor 1 (RB1) expression. Recent cytogenetic and molecular genetic studies have shown heterozygous deletions of 13q14, including the RB1 gene. SCL/PL can be successfully treated with simple excision, with a very low recurrence rate. Knowledge of these peculiar tumors is important because it can mimic a variety of benign and malignant soft-tissue tumors. This review provides an updated overview of the clinical, radiological, histopathological, cytogenetic, and molecular genetic features of SCL/PL.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.