Evidence map›Paper›PMID 37168906›Full record

ArticleJPGN reports2022

Evaluation of Hepatitis in Pediatric Patients With Presumed Nonalcoholic Fatty Liver Disease.

Fat'hiya Al-Harthy, Neha Kamath, Lee Hill, Jelena Popov, Allison Bossert, Herbert Brill, Nikhil Pai

Abstract read
In one paragraph

Article in JPGN reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fat'hiya Al-HarthyFrom the Department of Pediatrics, Division of Gastroenterology and Nutrition, McMaster University, Hamilton, Canada.
Neha KamathFaculty of Science, University of Western Ontario, London, Canada.
Lee HillDepartment of Pediatrics, Division of Gastroenterology and Nutrition, McMaster University, Hamilton, Canada.
Jelena PopovDepartment of Pediatrics, Division of Gastroenterology and Nutrition, McMaster University, Hamilton, Canada.
Allison BossertPediatric Gastroenterology and Nutrition, Hamilton Health Sciences Corporation (McMaster Children's Hospital), Hamilton, Canada.
Herbert BrillDepartment of Pediatrics, Division of Gastroenterology and Nutrition, McMaster University, Hamilton, Canada.
Nikhil PaiDepartment of Pediatrics, Division of Gastroenterology and Nutrition, McMaster University, Hamilton, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In 2017, the North American Society of Pediatric Gastroenterology, Hepatology and Nutrition published clinical practice guidelines for the assessment and diagnosis of nonalcoholic fatty liver disease (NAFLD). We determined how frequently these investigations suggest an alternate etiology for chronic hepatitis in 8- to 17-year-old patients with body mass index >85%, elevated alanine aminotransferase and radiographic steatosis, and rates of adherence to 2017 guidelines. Methods: We conducted a retrospective chart review of patients presenting to McMaster Children's Hospital from 2017-2020 for evaluation of suspected NAFLD. Bloodwork was reviewed. Results: Ninety-five patients met inclusion criteria. Abnormal bloodwork that required further testing was found in 28.4%; a different chronic liver disease was ultimately diagnosed in 11.6%. Only 9.5% received comprehensive, additional bloodwork for other causes of liver disease. Conclusion: A high proportion of patients evaluated for suspected NAFLD had bloodwork possibly suggesting an alternate diagnosis. Comprehensive testing was infrequently performed. These results reinforce the importance of maintaining a differential diagnosis among children presumed to have NAFLD.

Indexed as

chronic hepatitisguidelinesNAFLDpediatrictesting

Identifiers

PMID37168906
PMCPMC10158344

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.