Evidence map›Paper›PMID 37168856›Full record

ArticleFrontiers in immunology2023

ATRA treatment slowed P-selectin-mediated rolling of flowing HL60 cells in a mechano-chemical-dependent manner.

Xiaoting Dong, Shiping Peng, Yingchen Ling, Bing Huang, Wenjian Tu, Xiaoxi Sun, Quhuan Li, Ying Fang, Jianhua Wu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Cetyl All-International journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Xiaoting DongInstitute of Mechanics/School of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.
Shiping PengInstitute of Mechanics/School of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.
Yingchen LingInstitute of Mechanics/School of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.
Bing HuangInstitute of Mechanics/School of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.
Wenjian TuInstitute of Mechanics/School of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.
Xiaoxi SunInstitute of Mechanics/School of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.
Quhuan LiInstitute of Mechanics/School of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.
Ying FangInstitute of Mechanics/School of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.
Jianhua WuInstitute of Mechanics/School of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.
Institute of Mechanics · CNNanfang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

All-trans retinoic acid (ATRA)-induced differentiation of acute promyelocytic leukemia (APL) toward granulocytes may trigger APL differentiation syndrome (DS), but there is less knowledge about the mechano-chemical regulation mechanism of APL DS under the mechano-microenvironment. We found that ATRA-induced changes in proliferation, morphology, and adhesive molecule expression levels were either dose or stimulus time dependent. An optimal ATRA stimulus condition for differentiating HL60 cells toward neutrophils consisted of 1 × 10

Indexed as

Leukemia, Promyelocytic, AcuteP-SelectinCD18 AntigensHL-60 CellsHumansTretinoinCD18 AntigensP-SelectinTretinoinAPL DSATRAcell adhesiondifferentiationfluid shear stressHL60 cellneutrophils

Identifiers

PMID37168856
PMCPMC10164934
OpenAlexW4366827712

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.