Evidence map›Paper›PMID 37168508›Full record

ReviewFrontiers in genetics2023

Features of CFTR mRNA and implications for therapeutics development.

JaNise J Jackson, Yiyang Mao, Tyshawn R White, Catherine Foye, Kathryn E Oliver

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Lentiviral Gene Therapy for Cystic Fibrosis: A Promising Approach and First-in-Human Trial.American journal of respiratory and critical care medicine · 2024
    Review
  7. Cystic Fibrosis: A Journey through Time and Hope.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

JaNise J JacksonDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.
Yiyang MaoDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.
Tyshawn R WhiteDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.
Catherine FoyeDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.
Kathryn E OliverDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.
Children's Healthcare of Atlanta · USEmory University · US

Funding

Modulation of ribosome velocity as a means to rescue refractory CF-causing variantsR00HL151965 · NHLBI · EMORY UNIVERSITY · PI OLIVER, KATHRYN E · 2021 to 2023
$747k
NHLBI NIH HHS R00 HL151965
6 · The paper itself

Abstract

Cystic fibrosis (CF) is an autosomal recessive disease impacting ∼100,000 people worldwide. This lethal disorder is caused by mutation of the

Indexed as

antisense oligonucleotideCFTRmiRNAmRNA stabilitypeptide nucleic acid (PNA)readthrough compoundsuppressor tRNAsynonymous single nucleotide polymorphism

Identifiers

PMID37168508
PMCPMC10165737
OpenAlexW4366826106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.