Evidence map›Paper›PMID 37168496›Full record

ArticleFunction (Oxford, England)2023

Hypoxia Resistance Is an Inherent Phenotype of the Mouse Flexor Digitorum Brevis Skeletal Muscle.

Adam J Amorese, Everett C Minchew, Michael D Tarpey, Andrew T Readyoff, Nicholas C Williamson, Cameron A Schmidt, Shawna L McMillin, Emma J Goldberg, Zoe S Terwilliger, Quincy A Spangenburg and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Function (Oxford, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. What can ATP content tell us about Barth syndrome muscle phenotypes?Journal of translational genetics and genomics · 2025
    Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Adam J AmoreseDepartment of Physiology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.
Everett C MinchewDepartment of Physiology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.ORCID 0000-0003-1196-2865
Michael D TarpeyDepartment of Physiology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.
Andrew T ReadyoffEast Carolina Diabetes and Obesity Institute, East Carolina University, Greenville, NC 27834, USA.
Nicholas C WilliamsonDepartment of Physiology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.
Cameron A SchmidtDepartment of Biology, East Carolina University, Greenville, NC 27834, USA.
Shawna L McMillinDepartment of Kinesiology, East Carolina University, Greenville, NC 27858, USA.
Emma J GoldbergDepartment of Physiology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.
Zoe S TerwilligerDepartment of Physiology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.
Quincy A SpangenburgDepartment of Physiology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.
Carol A WitczakDepartment of Anatomy, Cell Biology, and Physiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Jeffrey J BraultDepartment of Anatomy, Cell Biology, and Physiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
E Dale AbelDavid Geffen School of Medicine, Department of Medicine, University of California, Los Angeles, CA 90095, USA.
Joseph M McClungDepartment of Physiology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.
Kelsey H Fisher-WellmanDepartment of Physiology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.ORCID 0000-0002-0300-829X
Espen E SpangenburgDepartment of Physiology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.
East Carolina University · USIndiana Hemophilia and Thrombosis Center · USUniversity of California, Los Angeles · US

Funding

Variant Determinants of African American Limb Pathology in Peripheral Arterial DiseaseR01HL157659 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MCCLUNG, JOSEPH MATTHEW · 2021 to 2024
$2.6M
Calmodulin Kinases and Control of Skeletal Muscle Glucose MetabolismR01DK103562 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI WITCZAK, CAROL ANN · 2015 to 2019
$1.7M
BRCA1 is necessary for optimal skeletal muscle functionR01AR066660 · NIAMS · EAST CAROLINA UNIVERSITY · PI SPANGENBURG, ESPEN E · 2015 to 2019
$1.6M
CELLULAR ENERGETICS AS A REGULATOR OF MUSCLE MASS AND MITOCHONDRIAL CONTENT DURING MUSCLE ATROPHYR01AR070200 · NIAMS · INDIANA UNIVERSITY INDIANAPOLIS · PI BRAULT, JEFFREY J · 2017 to 2021
$1.6M
Walk this way: leveraging of a unique skeletal muscle that is resistant to ischemic injuryR61AR078100 · NIAMS · EAST CAROLINA UNIVERSITY · PI SPANGENBURG, ESPEN E · 2020 to 2021
$739k
Role of FK506-Binding Protein 3 (FKBP3) as a Novel Regulator of Skeletal Muscle Protein SynthesisR21AR081593 · NIAMS · INDIANA UNIVERSITY INDIANAPOLIS · PI WITCZAK, CAROL ANN · 2022 to 2023
$384k
Walk this way: leveraging of a unique skeletal muscle that is resistant to ischemic injuryR33AR078100 · NIAMS · EAST CAROLINA UNIVERSITY · PI SPANGENBURG, ESPEN E · 2023 to 2023
$378k
NHLBI NIH HHS R01 HL157659NIAMS NIH HHS R01 AR066660NIAMS NIH HHS R01 AR070200NIAMS NIH HHS R21 AR081593NIAMS NIH HHS R33 AR078100NIAMS NIH HHS R61 AR078100NIDDK NIH HHS R01 DK103562
6 · The paper itself

Abstract

The various functions of skeletal muscle (movement, respiration, thermogenesis, etc.) require the presence of oxygen (O

Indexed as

HypoxiaMuscle, SkeletalAnimalsGlucose Transporter Type 1MammalsMiceMuscular AtrophyOxygenPhenotypeGlucose Transporter Type 1Oxygenhypoxiaischemiamousephenotyperesistanceskeletal muscle

Identifiers

PMID37168496
PMCPMC10165545
OpenAlexW4353082943

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.