Evidence map›Paper›PMID 37168480›Full record

ArticleJPGN reports2022

Unusual Presentation of Cow's Milk Protein Allergy.

Samantha Cresoe, Aniruddh Setya, Genie Beasley, David Hernandez Gonzalo, Albert Chan

Abstract readCase Reports
In one paragraph

Article in JPGN reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Cow milk protein allergy mimics in infancy.World journal of clinical pediatrics · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Samantha CresoeFrom the Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL.
Aniruddh SetyaDepartment of Pediatric Gastroenterology, Kidz Medical Services, Miami, FL.
Genie BeasleyFrom the Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL.
David Hernandez GonzaloDepartment of Pathology, University of Florida College of Medicine, Gainesville, FL.
Albert ChanFrom the Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cow's milk protein allergy (CMPA) is an abnormal immunologic response to bovine protein that can result in various gastrointestinal and cutaneous manifestations including diarrhea, failure to thrive, malabsorption, and even protein-losing enteropathy. We describe a case of a 7-month-old breastfed male who presented with severe atopic dermatitis, emesis, oily diarrhea, failure to thrive, electrolyte disturbance, and hemodynamic instability. Following stabilization, additional evaluation revealed concern for abetalipoproteinemia. Ultimately, the patient's symptoms resolved with introduction of an elemental formula and returned with reinitiation of cow's milk protein, confirming the diagnosis of severe CMPA. It is important for the general practitioner to be aware of the various presentations and have a high index of suspicion for CMPA as no symptom or diagnostic test is pathognomonic for diagnosis. Even though it can mimic other causes of malabsorption, a trial with extensively hydrolyzed or elemental formula should be attempted before undertaking invasive testing.

Indexed as

abetalipoproteinemiacow's milk protein allergyfailure to thrive

Identifiers

PMID37168480
PMCPMC10158318

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.