Evidence map›Paper›PMID 37168442›Full record

ArticleFrontiers in virology (Lausanne, Switzerland)2021

In vivo infection dynamics and human adaptive changes of SIVsm-derived viral siblings SIVmac239, SIV

James Z Curlin, Kimberly Schmitt, Leila Remling-Mulder, Ryan Moriarty, John J Baczenas, Kelly Goff, Shelby O'Connor, Mark Stenglein, Preston A Marx, Ramesh Akkina

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in virology (Lausanne, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

James Z CurlinDepartment of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, USA.
Kimberly SchmittDepartment of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, USA.
Leila Remling-MulderDepartment of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, USA.
Ryan MoriartyDepartment of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
John J BaczenasDepartment of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
Kelly GoffDepartment of Tropical Medicine, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA.
Shelby O'ConnorDepartment of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
Mark StengleinDepartment of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, USA.
Preston A MarxDepartment of Tropical Medicine, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA.
Ramesh AkkinaDepartment of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, USA.
Colorado State University · USUniversity of Wisconsin–Madison · USTulane University · US

Funding

WNPRC Supplemental Request for Nonhuman Primate Enclosures to Equip HIV/AIDS-Related Research FacilitiesP51OD011106 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI Dorota A. Grejner-Brzezinska · 2012 to 2026
$150.7M
Tulane NPRC SPF Sheltered Outdoor Enclosure ExpansionP51OD011104 · OD · TULANE UNIVERSITY OF LOUISIANA · PI L Lee HAMM · 2012 to 2026
$142.4M
NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
An Ultrasensitive In Vivo Latent HIV Viral Outgrowth Assay Using Humanized MiceR01AI120021 · NIAID · COLORADO STATE UNIVERSITY · PI AKKINA, RAMESH · 2015 to 2019
$3.4M
Modeling the molecular evolution of SIV to HIV using humanized miceR01AI123234 · NIAID · COLORADO STATE UNIVERSITY · PI AKKINA, RAMESH · 2016 to 2020
$2.4M
Training Program for Antiretroviral Discovery, Evaluation and Application Research (ADEAR)T32AI150547 · NIAID · UNIVERSITY OF COLORADO DENVER · PI Joshua Adam Barocas, Kristine Mace Erlandson · 2020 to 2026
$1.3M
NCATS NIH HHS UL1 TR002535NIAID NIH HHS R01 AI120021NIAID NIH HHS R01 AI123234NIAID NIH HHS T32 AI150547NIH HHS P51 OD011104NIH HHS P51 OD011106
6 · The paper itself

Abstract

Simian immunodeficiency virus native to sooty mangabeys (SIVsm) is believed to have given rise to HIV-2 through cross-species transmission and evolution in the human. SIVmac239 and SIV

Indexed as

A dual purpose humanized mouse model for HIV and SIV researchHIV origins and evolution from SIVorigin of human pathogens in NHPorigins of human pandemic virusesSIV cross-species transmissionSIV evolution into HIV-2SIVmac and SIVB670 pathogenesis and evolution in humanized miceviral adaptive changes and evolution

Identifiers

PMID37168442
PMCPMC10168645
OpenAlexW4205806402

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.