Evidence map›Paper›PMID 37168396›Full record

ArticleReproductive medicine and biology

Fatty acid supplementation into warming solutions improves pregnancy outcomes after single vitrified-warmed cleavage stage embryo transfers.

Ayumi Amagai, Kenji Ezoe, Tetsuya Miki, Kiyoe Shimazaki, Tadashi Okimura, Keiichi Kato

Abstract read
In one paragraph

Article in Reproductive medicine and biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ayumi AmagaiKato Ladies Clinic Tokyo Japan.
Kenji EzoeKato Ladies Clinic Tokyo Japan.ORCID https://orcid.org/0000-0002-3778-2259
Tetsuya MikiKato Ladies Clinic Tokyo Japan.ORCID https://orcid.org/0000-0003-0563-5358
Kiyoe ShimazakiKato Ladies Clinic Tokyo Japan.
Tadashi OkimuraKato Ladies Clinic Tokyo Japan.
Keiichi KatoKato Ladies Clinic Tokyo Japan.ORCID https://orcid.org/0000-0002-1394-4532

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study aimed to examine the embryonic development of human 4-cell stage embryos after warming with fatty acids (FAs) and to assess the pregnancy outcomes after single vitrified-warmed cleavage stage embryo transfers (SVCTs). Methods: Experimental study: A total of 217 discarded, vitrified human 4-cell stage embryos donated for research by consenting couples were used. The embryos were warmed using the fatty acid (FA)-supplemented solutions (FA group) or nonsupplemented solutions (control group). The developmental rate, morphokinetics, and outgrowth competence were analyzed. Clinical study: The treatment records of women undergoing SVCT in natural cycles between April and September 2022 were retrospectively analyzed (April-June 2022, control group; July-September 2022, FA group). Results: Experimental study: The rate of morphologically good blastocysts was significantly higher in the FA group than in the control group ( Conclusions: Fatty acid-supplemented warming solutions effectively improve embryo development to the blastocyst stage and pregnancy outcomes after SVCTs.

Indexed as

embryonic developmentembryo transferfatty acid supplementationmorphokineticspregnancy

Identifiers

PMID37168396
PMCPMC10165886

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.