Evidence map›Paper›PMID 37168365›Full record

ArticleFrontiers in oncology2023

Laura Schubert, Andrew Elliott, Anh T Le, Adriana Estrada-Bernal, Robert C Doebele, Emil Lou, Hossein Borghaei, Michael J Demeure, Razelle Kurzrock, Joshua E Reuss and 7 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Clinically actionable molecular alterations in Rb-retained small cell lung carcinoma variants.Virchows Archiv : an international journal of pathology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Oncogenic gene fusions in cancer: from biology to therapy.Signal transduction and targeted therapy · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. PRESSING Need of Precision Care in HER2-Positive Colorectal Cancer: The ELEPHANT in the Room.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
    Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 10 institutions in 1 country.

Laura SchubertDepartment of Medicine, Division of Medical Oncology, University of Colorado School of Medicine, Denver, CO, United States.
Andrew ElliottCARIS Life Sciences, Irving, TX, United States.
Anh T LeDepartment of Medicine, Division of Medical Oncology, University of Colorado School of Medicine, Denver, CO, United States.
Adriana Estrada-BernalDepartment of Medicine, Division of Medical Oncology, University of Colorado School of Medicine, Denver, CO, United States.
Robert C DoebeleDepartment of Medicine, Division of Medical Oncology, University of Colorado School of Medicine, Denver, CO, United States.
Emil LouDepartment of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota School of Medicine, Minneapolis, MN, United States.
Hossein BorghaeiDepartment of Hematology/Oncology, Fox Chase Cancer Center, Philadelphia, PA, United States.
Michael J DemeureHoag Memorial Hospital Presbyterian, Center for Applied Genomic Technologies, Newport Beach, CA, United States.
Razelle KurzrockDepartment of Medicine, University of California San Diego, La Jolla, CA, United States.
Joshua E ReussDepartment of Medicine, Georgetown University, Washington, DC, United States.
Sai-Hong Ignatius OuDepartment of Medicine, Division of Hematology/Oncology, University of California Irvine School of Medicine, Orange, CA, United States.
David R BraxtonHoag Memorial Hospital Presbyterian, Department of Pathology and Laboratory Medicine, Newport Beach, CA, United States.
Christian A ThomasNew New England Cancer Specialists, Scarborough, ME, United States.
Sourat DarabiHoag Memorial Hospital Presbyterian, Center for Applied Genomic Technologies, Newport Beach, CA, United States.
Wolfgang Michael KornDepartment of Pathology and Laboratory Medicine, Cancer Center at Brown University, Providence, RI, United States.
Wafik S El-DeiryCancer Center at Brown University, Department of Pathology and Laboratory Medicine, Providence, RI, United States.
Stephen V LiuDepartment of Medicine, Georgetown University, Washington, DC, United States.
University of Colorado Denver · USHoag Memorial Hospital Presbyterian · USBrown University · USGeorgetown University · USCaris Life Sciences (United States) · USFox Chase Cancer Center · USNew England Cancer Specialists · USUniversity of California, Irvine · USUniversity of California, San Diego · USUniversity of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Gene fusions involving receptor tyrosine kinases (RTKs) define an important class of genomic alterations with many successful targeted therapies now approved for Materials and methods: We analyzed tumor samples submitted to Caris Life Sciences (n=64,354), as well as the TCGA (n=10,967), MSK IMPACT (n=10,945) and AACR GENIE (n=96,324) databases for evidence of Results: In total, we identified 1,251 Conclusions: We found that

Indexed as

500 ERBB family fusions across cancer typesEGFRERBB2ERBB4 words: 3gene fusiononcogene

Identifiers

PMID37168365
PMCPMC10164992
OpenAlexW4366827903

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.