Evidence map›Paper›PMID 37168331›Full record

ArticleAmerican journal of cancer research2023

Identification of hub genes associated with head and neck squamous cell carcinoma by integrated bioinformatics approach and RNA-seq validation analysis.

Amir Shabeer, Sara Mustafa, Rimsha Sadia Bukhari, Mostafa A Abdel-Maksoud, Saeedah Musaed Almutairi, Wahidah H Al-Qahtani, Khushboo Chandio, Nazima Yousaf Khan, Jaweria Gul, Mohammed Aufy

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In one paragraph

Article in American journal of cancer research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 76% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Amir ShabeerIsra University Hyderabad Sindh, Pakistan.
Sara MustafaTehsil Headquarter (THQ) Rojhan Rajanpur, Pakistan.
Rimsha Sadia BukhariFatima Jinnah Medical University Lahore, Pakistan.
Mostafa A Abdel-MaksoudDepartment of Botany and Microbiology, College of Science, King Saud University Riyadh P.O. 2455, Riyadh 11451, Saudi Arabia.
Saeedah Musaed AlmutairiDepartment of Botany and Microbiology, College of Science, King Saud University Riyadh P.O. 2455, Riyadh 11451, Saudi Arabia.
Wahidah H Al-QahtaniDepartment of Food Sciences & Nutrition, College of Food and Agricultural Sciences, King Saud University P.O. Box 270677, Riyadh 11352, Saudi Arabia.
Khushboo ChandioPeoples Nursing School LUMHS Jamshoro, Pakistan.
Nazima Yousaf KhanInstitute of Biochemistry, University of Balochistan Quetta, Pakistan.
Jaweria GulShaheed Benazir Bhutto University Sheringal, Dir Upper, Pakistan.
Mohammed AufyDepartment of Pharmaceutical Sciences, Division of Pharmacology and Toxicology, University of Vienna Vienna, Austria.
Fatima Jinnah Medical University · PKShaheed Benazir Bhutto University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Head and neck squamous cell carcinoma (HNSC) is one of the most lethal malignancies around the globe. Due to its complex nature, the diagnostic and prognostic signatures of HNSC remain poorly understood. This study was launched to identify signature genes and their signaling pathways related to the development of HNSC. In the current study, we retrieved the GSE53819 dataset from the Gene Expression Omnibus (GEO) database to determine the differentially expressed genes (DEGs) using the "Limma" R package. Adjusted

Indexed as

biomarkergene expressionHNSCtherapeutic target

Identifiers

PMID37168331
PMCPMC10164813
OpenAlexW4376223940

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.