Evidence map›Paper›PMID 37168272›Full record

ArticleDEN open2024

Analyses of cytokine gene expression and fecal microbiota in a patient with Cronkhite-Canada syndrome successfully treated with prednisolone.

Hajime Honjo, Yasuhiro Masuta, Yasuo Otsuka, Sho Masaki, Kosuke Minaga, Masatoshi Kudo, Tomohiro Watanabe

Abstract readCase Reports
In one paragraph

Article in DEN open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hajime HonjoDepartment of Gastroenterology and Hepatology Kindai University Faculty of Medicine Osaka Japan.
Yasuhiro MasutaDepartment of Gastroenterology and Hepatology Kindai University Faculty of Medicine Osaka Japan.
Yasuo OtsukaDepartment of Gastroenterology and Hepatology Kindai University Faculty of Medicine Osaka Japan.
Sho MasakiDepartment of Gastroenterology and Hepatology Kindai University Faculty of Medicine Osaka Japan.
Kosuke MinagaDepartment of Gastroenterology and Hepatology Kindai University Faculty of Medicine Osaka Japan.
Masatoshi KudoDepartment of Gastroenterology and Hepatology Kindai University Faculty of Medicine Osaka Japan.
Tomohiro WatanabeDepartment of Gastroenterology and Hepatology Kindai University Faculty of Medicine Osaka Japan.ORCID https://orcid.org/0000-0002-6175-8064

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although prednisolone treatment is effective in Cronkhite-Canada syndrome (CCS), its mechanisms of action are poorly understood. We performed analyses of cytokine expression and fecal microbiota in a patient with the concurrent occurrence of CCS and rectal cancer, in whom regression of polyposis was achieved by prednisolone. Regression of CCS polyps was accompanied by downregulation of proinflammatory cytokine expression and alterations in microbiota composition; a decrease in

Indexed as

Cronkhite–Canada syndromecytokinemicrobiotapolyposisprednisolone

Identifiers

PMID37168272
PMCPMC10165462

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.