Evidence map›Paper›PMID 37168028›Full record

ReviewOTA international : the open access journal of orthopaedic trauma2023

Fracture healing-orthobiologics: from basic science to clinical application.

Joey P Johnson, Jaimo Ahn, Douglas R Dirschl, John J Wixted, Andrew R Evans

Abstract readReview
In one paragraph

Review in OTA international : the open access journal of orthopaedic trauma, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joey P JohnsonDepartment of Orthopedic Surgery, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL.
Jaimo AhnDepartment of Orthopaedic Surgery, University of Michigan, Ann Arbor, MI.
Douglas R DirschlDepartment of Orthopaedic Surgery and Rehabilitation Medicine, University of Chicago, Chicago, IL.
John J WixtedBeth Israel Deaconess Medical Center, Boston, MA; and.
Andrew R EvansDepartment of Orthopedics, The Warren Alpert School of Medicine, Brown University, Providence, RI.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Orthopaedics as a field and a profession is fundamentally concerned with the treatment of musculoskeletal disease, in all of its many forms. Our collective understanding of the cellular mechanisms underlying musculoskeletal pathology resulting from injury continues to evolve, opening novel opportunities to develop orthobiologic treatments to improve care. It is a long path to move from an understanding of cellular pathology to development of successful clinical treatment, and this article proposes to discuss some of the challenges to achieving translational therapies in orthopaedics. The article will focus on challenges that clinicians will likely face in seeking to bring promising treatments forward to clinical practice and strategies for improving success in translational efforts.

Indexed as

basic scienceorthobiologicsresearch

Identifiers

PMID37168028
PMCPMC10166332

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.