ReviewNeuron2023
20 years of the default mode network: A review and synthesis.
Review in Neuron, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 466 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
466 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- A systematic review on dysconnectivity in face and emotion processing networks in schizophrenia.Cognitive, affective & behavioral neuroscience · 2026Pooled it
- The Boredom-ADHD Nexus: A Narrative and Meta-Analytic Review of the Evidence.Clinical child and family psychology review · 2026Pooled it
- Structural and Functional Neuroimaging Findings in Fibromyalgia: A Systematic Review.European journal of pain (London, England) · 2026Pooled it
- The Use of Psychedelics in the Treatment of Adult ADHD: A Systematic and Mechanistic Review.International journal of molecular sciences · 2026Pooled it
- Cognitive and neuropsychological correlates of the attention training technique: a systematic review and evidence synthesis.Frontiers in psychiatry · 2026Pooled it
- Functional MRI evidence of brain alterations in premenstrual dysphoric disorder: a systematic review.Frontiers in psychiatry · 2026Pooled it
- Testosterone modulation of default mode network and its effects on cognitive function and mood in humans: a systematic review.Frontiers in neuroscience · 2026Pooled it
- Ketamine's impact on rumination-related brain dynamics: insights from a randomized controlled fMRI trial.Translational psychiatry · 2026Trial
- Trial
- Aerobic Exercise and Subthreshold Depressive Symptoms in Adolescents: Secondary Analysis of a Randomized Clinical Trial.JAMA network open · 2026Trial
- Electrocortical Indices of Default Mode Network-Related Activity in ADHD and Modulation Through Mindfulness-Based Cognitive Therapy.Brain topography · 2026Trial
- Remote cognitive-motor dual-task training and cognition in mild cognitive impairment: a randomized controlled trial.Scientific reports · 2026Trial
- rTMS modulates early AD progression via synergistic brain network reorganization and peripheral biomarker dynamics.GeroScience · 2026Trial
- Efficacy and safety of transcranial alternating current stimulation in adults with attention deficit hyperactivity disorder: a double-blind randomized sham-controlled trial.Molecular psychiatry · 2026Trial
- Brain functional basis of the association between positive expectation and acupuncture efficacy in knee osteoarthritis.Brain imaging and behavior · 2026Trial
- Hierarchical neural variability reveals adaptive and maladaptive mechanisms of non-suicidal self-injury.Molecular psychiatry · 2026Article
- Reward sensitivity is negatively associated with future self-continuity: the mediation role of functional connectivity between the dorsomedial prefrontal cortex and ventrolateral prefrontal cortex.Brain structure & function · 2026Article
- EOAD-Signature Atrophy Predicts Dementia in Early-Onset MCI due to Alzheimer Disease: An MRI-Based Prognostic Biomarker.Neurology · 2026Article
- Nociceptive responses and resting-state functional connectivity of the human midbrain tegmentum.Brain structure & function · 2026Article
- Large-Scale Cerebellar-Cerebral Network Alterations Underlying Impaired Social Predictive Processing in Cerebellar Neurodegeneration.Cerebellum (London, England) · 2026Article
406 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
The discovery of the default mode network (DMN) has revolutionized our understanding of the workings of the human brain. Here, I review developments that led to the discovery of the DMN, offer a personal reflection, and consider how our ideas of DMN function have evolved over the past two decades. I summarize literature examining the role of the DMN in self-reference, social cognition, episodic and autobiographical memory, language and semantic memory, and mind wandering. I identify unifying themes and propose new perspectives on the DMN's role in human cognition. I argue that the DMN integrates and broadcasts memory, language, and semantic representations to create a coherent "internal narrative" reflecting our individual experiences. This narrative is central to the construction of a sense of self, shapes how we perceive ourselves and interact with others, may have ontogenetic origins in self-directed speech during childhood, and forms a vital component of human consciousness.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.