Evidence map›Paper›PMID 37167796›Full record

ArticleDrug and alcohol dependence2023

To be aware, or to accept, that is the question: Differential roles of awareness of automaticity and pain acceptance in opioid misuse.

Anna Parisi, Aleksandra E Zgierska, Cindy A Burzinski, Robert P Lennon, Robert N Jamison, Yoshio Nakamura, Bruce Barrett, Robert R Edwards, Eric L Garland

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Anna ParisiUniversity of Utah, Center on Mindfulness and Integrative Health Intervention Development, College of Social Work, 395 1500 E, Salt Lake City, UT84112, United States.
Aleksandra E ZgierskaPennsylvania State University College of Medicine Department of Family and Community Medicine, 90 Hope Drive, Hershey, PA17033, United States.
Cindy A BurzinskiUniversity of Wisconsin-Madison, School of Medicine and Public Health, Department of Family Medicine and Community Health, 1100 Delaplaine Court, Madison, WI53715, United States.
Robert P LennonPennsylvania State University College of Medicine Department of Family and Community Medicine, 90 Hope Drive, Hershey, PA17033, United States.
Robert N JamisonHarvard Medical School, Brigham and Women's Hospital, Departments of Anesthesiology, Perioperative and Pain Medicine and Psychiatry, 850 Boylston Street, Chestnut Hill, MA02467, United States.
Yoshio NakamuraUniversity of Utah School of Medicine, Department of Anesthesiology, Division of Pain Medicine, Pain Research Center, 615 Arapeen Drive, Suite 200, Salt Lake City, UT84108, United States.
Bruce BarrettUniversity of Wisconsin-Madison, School of Medicine and Public Health, Department of Family Medicine and Community Health, 1100 Delaplaine Court, Madison, WI53715, United States.
Robert R EdwardsHarvard Medical School, Brigham and Women's Hospital, Departments of Anesthesiology, Perioperative and Pain Medicine and Psychiatry, 850 Boylston Street, Chestnut Hill, MA02467, United States.
Eric L GarlandUniversity of Utah, Center on Mindfulness and Integrative Health Intervention Development, College of Social Work, 395 1500 E, Salt Lake City, UT84112, United States. Electronic address: eric.garland@socwk.utah.edu.
University of Utah · USBrigham and Women's Hospital · USPennsylvania State University · USUniversity of Wisconsin–Madison · US

Funding

Motivational Interviewing and Mindfulness-Oriented Recovery Enhancement for Tobacco Dependence and Other Drug use in Methadone TreatmentR01DA057631 · NIDA · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Nina Cooperman, Eric Lee Garland · 2022 to 2026
$3.8M
Implementation and Effectiveness of Mindfulness Oriented Recovery Enhancement as an Adjunct to Methadone Treatment for Opioid Use DisorderR01DA056537 · NIDA · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Nina Cooperman, Eric Lee Garland · 2022 to 2026
$3.4M
Analgesic and Opioid Sparing Brain Mechanisms of Mindfulness-Oriented Recovery Enhancement for Chronic Low Back PainR01AT011772 · NCCIH · UNIVERSITY OF UTAH · PI Eric Lee Garland, Fadel Zeidan · 2022 to 2026
$3.0M
NCCIH NIH HHS R01 AT011772NIDA NIH HHS R01 DA056537NIDA NIH HHS R01 DA057631Patient-Centered Outcomes Research Institute OPD-1601-33860
6 · The paper itself

Abstract

backgroundIndividuals with chronic low back pain (CLBP) are commonly prescribed long-term opioid therapy (LTOT) for analgesia, placing this population at increased risk for opioid misuse and opioid use disorder. Acceptance of aversive experiences (e.g., chronic pain) and awareness of automatic thoughts and behaviors (i.e., automaticity) are two facets of dispositional mindfulness that may serve as protective mechanisms against opioid misuse risk. Therefore, the aim of the current study was to examine the differential contributions of these constructs to opioid misuse risk among adults with CLBP receiving LTOT.

methodsData were obtained from a sample of 770 adults with opioid-treated CLBP. Bivariate correlations and hierarchical linear regression analyses were used to determine whether chronic pain acceptance and awareness of automatic thoughts and behaviors explained a statistically significant portion of variance in opioid misuse risk after accounting for the effects of other relevant confounders.

resultsHierarchical regression results revealed that chronic pain acceptance and awareness of automatic thoughts and behaviors contributed a significant portion in the variance of opioid misuse risk. Awareness of automatic thoughts and behaviors was negatively associated with opioid misuse risk, such that individuals with lower levels of awareness of automaticity were at higher risk of opioid misuse. By contrast, pain acceptance was not associated with opioid misuse.

conclusionsFindings suggest that awareness of automaticity may buffer against opioid misuse risk. Interventions designed to strengthen awareness of automaticity (e.g., mindfulness-based interventions) might be especially efficacious among this population.

Indexed as

Chronic PainLow Back PainMindfulnessOpioid-Related DisordersAdultAffectAnalgesics, OpioidHumansAnalgesics, OpioidAcceptanceAutomaticityChronic painDispositional mindfulnessOpioidsTrait mindfulness

Identifiers

PMID37167796
PMCPMC10714486
OpenAlexW4366525583

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.