Evidence map›Paper›PMID 37167549›Full record

ArticleAmerican journal of respiratory and critical care medicine2023

A Large-Scale Exome-Wide Association Study Identifies Novel Germline Mutations in Lung Cancer.

Sipeng Shen, Zaiming Li, Yunke Jiang, Weiwei Duan, Hongru Li, Sha Du, Manel Esteller, Hongbing Shen, Zhibin Hu, Yang Zhao and 2 more

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. A trans-omics gene-smoking interaction study of lung cancer based on consortium data.American journal of respiratory and critical care medicine · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Lung Cancer Risk and Delivering on the Promise of the Genomic Era.American journal of respiratory and critical care medicine · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 5 countries.

Sipeng ShenDepartment of Biostatistics and.ORCID 0000-0003-0436-4736
Zaiming LiDepartment of Biostatistics and.
Yunke JiangDepartment of Biostatistics and.
Weiwei DuanDepartment of Bioinformatics, School of Biomedical Engineering and Informatics, and.
Hongru LiDepartment of Biostatistics and.
Sha DuDepartment of Biostatistics and.
Manel EstellerJosep Carreras Leukaemia Research Institute, Barcelona, Spain.
Hongbing ShenDepartment of Epidemiology, Center for Global Health, School of Public Health.
Zhibin HuDepartment of Epidemiology, Center for Global Health, School of Public Health.
Yang ZhaoDepartment of Biostatistics and.
David C ChristianiDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts; and.ORCID 0000-0002-0301-0242
Feng ChenDepartment of Biostatistics and.
Center for Personalized Cancer Treatment · NLJapan International Cooperation Agency · JPHarvard University · USInstitució Catalana de Recerca i Estudis Avançats · ESNanjing Medical University · CN

Funding

The Boston Lung Cancer Survival CohortU01CA209414 · NCI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI David C Christiani · 2017 to 2026
$12.2M
Statistical Methods for Analysis of Massive Genetic and Genomic Data in Cancer ResearchR35CA197449 · NCI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI XIHONG LIN · 2015 to 2026
$10.9M
NCI NIH HHS R35 CA197449NCI NIH HHS U01 CA209414
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ExomeLung NeoplasmsBayes TheoremGenetic Predisposition to DiseaseGenome-Wide Association StudyGerm-Line MutationHumansPolymorphism, Single Nucleotideexome sequencingexome-wide association studygermline mutationlung cancertrans-omics

Identifiers

PMID37167549
PMCPMC10395715
OpenAlexW4376128563

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.