Evidence map›Paper›PMID 37167393›Full record

ArticleScience (New York, N.Y.)2023

Effects of hunger on neuronal histone modifications slow aging in

K J Weaver, R A Holt, E Henry, Y Lyu, S D Pletcher

Open access · greenAbstract read
In one paragraph

Article in Science (New York, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
7.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 48 citations in OpenAlex.

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  12. Multi-Omics Analysis RevealsEcology and evolution · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

K J WeaverDepartment of Molecular and Integrative Physiology and Geriatrics Center, Biomedical Sciences and Research Building, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0003-2496-3568
R A HoltCollege of Literature, Science, and the Arts, Biomedical Sciences and Research Building, University of Michigan, Ann Arbor, MI 48109, USA.
E HenryProgram in Cellular and Molecular Biology, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0002-1972-6245
Y LyuDepartment of Molecular Biology & Biochemistry, Rutgers University, Piscataway, NJ 08855, USA.ORCID 0000-0002-4618-9043
S D PletcherDepartment of Molecular and Integrative Physiology and Geriatrics Center, Biomedical Sciences and Research Building, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0002-4812-3785
University of Michigan · USRutgers, The State University of New Jersey · US

Funding

Research Training in BiogerontologyT32AG000114 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SCOTT PLETCHER · 1985 to 2026
$12.4M
Modulation of aging by Sensory PerceptionR01AG030593 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PLETCHER, SCOTT · 2007 to 2025
$6.1M
Modulation of aging through mechanisms of nutrient demand and rewardR37AG051649 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SCOTT PLETCHER · 2021 to 2026
$2.3M
The role of neural signaling pathways in costs of reproduction on agingR01AG063371 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PLETCHER, SCOTT, PROMISLOW, DANIEL EDWARD · 2019 to 2023
$1.9M
Systems and methods for molecular dissection of socio-environmental effects on agingR33AG078428 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SCOTT PLETCHER · 2024 to 2026
$1.7M
Modulation of aging through mechanisms of nutrient demand and rewardR01AG051649 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PLETCHER, SCOTT · 2016 to 2020
$1.6M
NIA NIH HHS R01 AG030593NIA NIH HHS R01 AG051649NIA NIH HHS R01 AG063371NIA NIH HHS R33 AG078428NIA NIH HHS R37 AG051649NIA NIH HHS T32 AG000114
6 · The paper itself

Abstract

Hunger is an ancient drive, yet the molecular nature of pressures of this sort and how they modulate physiology are unknown. We find that hunger modulates aging in

Indexed as

AgingAmino Acids, Branched-ChainDrosophila melanogasterHistonesHungerNeuronsAnimalsHistone CodeAmino Acids, Branched-ChainHistones

Identifiers

PMID37167393
PMCPMC11837410
OpenAlexW4376128965

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.