ArticlePloS one2023
Resting heart rate is a population-level biomarker of cardiorespiratory fitness: The Fenland Study.
Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed, 34 citations in OpenAlex.
- Parkinson's disease, aerobic exercise and photobiomodulation: a randomised controlled trial.Journal of neural transmission (Vienna, Austria : 1996) · 2026Trial
- Autophagy Flux Is Remodeled Sex- and Cell Type-Specifically During Human Aging, and Is Linked to Reduced Physical Function in Older Adults.Aging cell · 2026Article
- Effects of Aerobic Exercise on Heart Rate Variability and C-Reactive Protein in Middle-Aged Adults With Normal Weight and Overweight/Obesity: A Pilot Study.Research in nursing & health · 2026Article
- Guidelines for rigor and reproducibility of heart rate variability within human cardiovascular research.American journal of physiology. Heart and circulatory physiology · 2026Review
- Prognostic role of resting heart rate in patients with colorectal cancer.Journal of gastrointestinal oncology · 2026Article
- Preoperative resting heart rate and colorectal cancer mortality: a robust association, but causality remains unestablished.Journal of gastrointestinal oncology · 2026Article
- Deep learning to predict left ventricular hypertrophy from the electrocardiogram.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026Article
- Domain-informed weight forecasting: leveraging behavioral and physiological sequences from wearables.Frontiers in public health · 2026Article
- The relation between physical activity and cardiac autonomic dysfunction in patients with chronic obstructive pulmonary disease.PloS one · 2026Article
- Improvements in body composition, functional capacity, and cardiovascular fitness: results of a workplace wellness program in the United Arab Emirates.Frontiers in sports and active living · 2026Article
- Enhancing physical fitness in older adults: a six-month medium intensity training intervention yields significant improvements.BMC sports science, medicine & rehabilitation · 2025Article
- Optimizing cardiorespiratory fitness after bariatric surgery - highly effective with very low adherence: HIT BAR randomized controlled trial.BMC sports science, medicine & rehabilitation · 2025Article
- Validation of nocturnal resting heart rate and heart rate variability in consumer wearables.Physiological reports · 2025Article
- Feasibility of Data Collection Via Consumer-Grade Wearable Devices in Adolescent Student Athletes: Prospective Longitudinal Cohort Study.JMIR formative research · 2025Article
- Association between resting heart rate and prognosis in patients with gastric cancer.Scientific reports · 2025Article
- A Systematic Review and Meta-Analysis on Aerobic Fitness Dynamics in Post-COVID-19 Athletes: Implications in the Return-to-Play Performance.Sports (Basel, Switzerland) · 2025Review
- The relationship between cardiorespiratory fitness and indices of fat mass and fat-free mass in adults.Frontiers in sports and active living · 2025Article
- Protecting the Heart in Motion: The Role of Physical Activity and Cardiorespiratory Fitness in Preventing Sudden Cardiac Death.Clinical Medicine Insights. Cardiology · 2025Review
- Unraveling the link between cardiorespiratory fitness and cancer: a state-of-the-art review.GeroScience · 2024Review
- Integrating Remote Photoplethysmography and Machine Learning on Multimodal Dataset for Noninvasive Heart Rate Monitoring.Sensors (Basel, Switzerland) · 2024Article
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 2 countries.
Funding
Abstract
introductionFew large studies have evaluated the relationship between resting heart rate (RHR) and cardiorespiratory fitness. Here we examine cross-sectional and longitudinal relationships between RHR and fitness, explore factors that influence these relationships, and demonstrate the utility of RHR for remote population monitoring.
methodsIn cross-sectional analyses (The UK Fenland Study: 5,722 women, 5,143 men, aged 29-65y), we measured RHR (beats per min, bpm) while seated, supine, and during sleep. Fitness was estimated as maximal oxygen consumption (ml⋅min-1⋅kg-1) from an exercise test. Associations between RHR and fitness were evaluated while adjusting for age, sex, adiposity, and physical activity. In longitudinal analyses (6,589 participant subsample), we re-assessed RHR and fitness after a median of 6 years and evaluated the association between within-person change in RHR and fitness. During the coronavirus disease-2019 pandemic, we used a smartphone application to remotely and serially measure RHR (1,914 participant subsample, August 2020 to April 2021) and examined differences in RHR dynamics by pre-pandemic fitness level.
resultsMean RHR while seated, supine, and during sleep was 67, 64, and 57 bpm. Age-adjusted associations (beta coefficients) between RHR and fitness were -0.26, -0.29, and -0.21 ml⋅kg-1⋅beat-1 in women and -0.27, -0.31, and -0.19 ml⋅kg-1⋅beat-1 in men. Adjustment for adiposity and physical activity attenuated the RHR-to-fitness relationship by 10% and 50%, respectively. Longitudinally, a 1-bpm increase in supine RHR was associated with a 0.23 ml⋅min-1⋅kg-1 decrease in fitness. During the pandemic, RHR increased in those with low pre-pandemic fitness but was stable in others.
conclusionsRHR is a valid population-level biomarker of cardiorespiratory fitness. Physical activity and adiposity attenuate the relationship between RHR and fitness.
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