Evidence map›Paper›PMID 37166745›Full record

ArticleOdontology2024

The effect of light compressive and tensile mechanical forces on SOST and POSTN expressions in human periodontal ligament cells: an in vitro study.

Nastaran Sharifi, Mohammad Sadegh Ahmad Akhoundi, Mahshid Hodjat, Nooshin Haghighipour, Setareh Kazemi Veysari

Abstract read
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In one paragraph

Article in Odontology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Nastaran SharifiDepartment of Orthodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0002-6277-0380
Mohammad Sadegh Ahmad AkhoundiDepartment of Orthodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran. ahmadakh@tums.ac.ir.ORCID http://orcid.org/0000-0002-9934-8386
Mahshid HodjatDental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Nooshin HaghighipourNational Cell Bank of Iran, Pasteur Institute of Iran, Tehran, Iran.
Setareh Kazemi VeysariDental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0003-3890-1747
Tehran University of Medical Sciences · IRPasteur Institute of Iran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodontal ligament (PDL) cells play an important role in mechanosensing and secretion of signaling molecules during bone remodeling. However, the regulatory mechanism is unknown. The aim of the present study is to investigate the expression pattern of periostin and sclerostin in response to orthodontic forces in periodontal ligament cells in vitro. PDL cells were isolated from extracted teeth and treated with compressive forces of 25 gr/cm

Indexed as

Core Binding Factor Alpha 1 SubunitPeriodontal LigamentAdaptor Proteins, Signal TransducingBiomarkersBone RemodelingCell Adhesion MoleculesCells, CulturedHumansPressureStress, MechanicalTooth Movement TechniquesAdaptor Proteins, Signal TransducingBiomarkersCell Adhesion MoleculesCore Binding Factor Alpha 1 SubunitPOSTN protein, humanSOST protein, humanGene expressionOrthodontic tooth movementPeriostinSclerostin

Identifiers

PMID37166745
OpenAlexW4376133585

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.