Evidence map›Paper›PMID 37166596›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2023

Comprehensive Survey of ChIP-Seq Datasets to Identify Candidate Iron Homeostasis Genes Regulated by Chromatin Modifications.

Yang Yu, Yuxin Wang, Zhujun Yao, Ziqin Wang, Zijun Xia, Joohyun Lee

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yang YuDivision of Natural and Applied Sciences, Duke Kunshan University, Jiangsu, China.
Yuxin WangDivision of Natural and Applied Sciences, Duke Kunshan University, Jiangsu, China.
Zhujun YaoDivision of Natural and Applied Sciences, Duke Kunshan University, Jiangsu, China.
Ziqin WangDivision of Natural and Applied Sciences, Duke Kunshan University, Jiangsu, China.
Zijun XiaDivision of Natural and Applied Sciences, Duke Kunshan University, Jiangsu, China.
Joohyun LeeDivision of Natural and Applied Sciences, Duke Kunshan University, Jiangsu, China. joohyun.lee@duke.edu.ORCID 0000-0003-1696-8991
Duke Kunshan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vital biochemical reactions including photosynthesis to respiration require iron, which should be tightly regulated. Although increasing evidence reveals the importance of epigenetic regulation in gene expression and signaling, the role of histone modifications and chromatin remodeling in plant iron homeostasis is not well understood. In this study, we surveyed publicly available ChIP-seq datasets of Arabidopsis wild-type and mutants defective in key enzymes of histone modification and chromatin remodeling and compared the deposition of epigenetic marks on loci of genes involved in iron regulation. Based on the analysis, we compiled a comprehensive list of iron homeostasis genes with differential enrichment of various histone modifications. This report will provide a resource for future studies to investigate epigenetic regulatory mechanisms of iron homeostasis in plants.

Indexed as

ArabidopsisChromatin Immunoprecipitation SequencingChromatinEpigenesis, GeneticHomeostasisIronChromatinIronArabidopsisChIP-SeqChromatin remodelingHistone modificationIron homeostasis

Identifiers

PMID37166596
OpenAlexW4376131956

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.