Evidence map›Paper›PMID 37166546›Full record

ArticleJournal of molecular histology2023

Lack of Rab27a attenuates foam cell formation and macrophage inflammation in uremic apolipoprotein E knockout mice.

Yan Shen, Yajuan Gao, Jiani Fu, Cui Wang, Yali Tang, Shengnan Chen, Yan Zhao

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Journal of molecular histology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yan ShenDepartment of Nephrology, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277, West Yanta Road, Yanta District, Shaanxi, 710061, Xi'an, China. shenyan66@126.com.
Yajuan GaoDepartment of Nephrology, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277, West Yanta Road, Yanta District, Shaanxi, 710061, Xi'an, China.
Jiani FuDepartment of Nephrology, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277, West Yanta Road, Yanta District, Shaanxi, 710061, Xi'an, China.
Cui WangDepartment of Nephrology, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277, West Yanta Road, Yanta District, Shaanxi, 710061, Xi'an, China.
Yali TangDepartment of Nephrology, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277, West Yanta Road, Yanta District, Shaanxi, 710061, Xi'an, China.
Shengnan ChenDepartment of Nephrology, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277, West Yanta Road, Yanta District, Shaanxi, 710061, Xi'an, China.
Yan ZhaoDepartment of Cardiovascular Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China.
First Affiliated Hospital of Xi'an Jiaotong University · CN

Funding

China scholarship fund Grant No. 201506285033Key Research and Development Program of Shaanxi Grant No. 2020KW-043National Natural Science Foundation of China Grant No. 81200541'PRO•Run' Fund of the Nephrology Group of CEBM KYS2021-03-02-9Shaanxi provincial health and family planning scientific research fund project, China Grant No. 2016D064the Fundamental Research Funds for the Central Universities Grant No. xjj2017047Xi'an science and technology project Grant No. 201805095YX3SF29
6 · The paper itself

Abstract

As the most common cardiovascular disease, atherosclerosis (AS), is a leading cause of high mortality in patients with chronic renal failure. Rab27a has been reported to regulate the progression of cardiovascular and renal diseases. Nevertheless, little studies investigated the role and mechanism of Rab27a in uremic-accelerated AS (UAAS). An animal model of UAAS was established in apolipoprotein E knockout (apoE

Indexed as

AtherosclerosisFoam CellsAnimalsApolipoproteinsApolipoproteins EInflammationMacrophagesMiceMice, KnockoutNF-kappa Brab27 GTP-Binding ProteinsApolipoproteinsApolipoproteins ENF-kappa BRab27a protein, mouserab27 GTP-Binding ProteinsAtherosclerosisFoam cellInflammationRab27aUremia

Identifiers

PMID37166546
OpenAlexW4376131814

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.