Evidence map›Paper›PMID 37166494›Full record

ArticleEuropean radiology2023

PET/MRI of hypoxia and vascular function in ER-positive breast cancer: correlations with immunohistochemistry.

Julia C Carmona-Bozo, Roido Manavaki, Jodi L Miller, Cara Brodie, Corradina Caracò, Ramona Woitek, Gabrielle C Baxter, Martin J Graves, Tim D Fryer, Elena Provenzano and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Targeting tumor transition windows.Exploration of targeted anti-tumor therapy · 2026
    Review
  4. Review
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Julia C Carmona-BozoDepartment of Radiology, School of Clinical Medicine, University of Cambridge, Box 218 - Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.
Roido ManavakiDepartment of Radiology, School of Clinical Medicine, University of Cambridge, Box 218 - Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.
Jodi L MillerCancer Research UK - Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.
Cara BrodieCancer Research UK - Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.
Corradina CaracòDepartment of Radiology, School of Clinical Medicine, University of Cambridge, Box 218 - Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.
Ramona WoitekDepartment of Radiology, School of Clinical Medicine, University of Cambridge, Box 218 - Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.
Gabrielle C BaxterDepartment of Radiology, School of Clinical Medicine, University of Cambridge, Box 218 - Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.
Martin J GravesDepartment of Radiology, School of Clinical Medicine, University of Cambridge, Box 218 - Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.
Tim D FryerWolfson Brain Imaging Centre, Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Box 65 - Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.
Elena ProvenzanoCancer Research UK - Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK.
Fiona J GilbertDepartment of Radiology, School of Clinical Medicine, University of Cambridge, Box 218 - Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK. fjg28@cam.ac.uk.ORCID http://orcid.org/0000-0002-0124-9962
University of Cambridge · GBCancer Research UK · GB

Funding

Cancer Research UK CRI_CORE_HIISH_2324Cancer Research UK Cambridge Institute, University of Cambridge C197/A16465
6 · The paper itself

Abstract

objectivesTo explore the relationship between indices of hypoxia and vascular function from

methodsWomen aged  > 18 years with biopsy-confirmed, treatment-naïve primary ER + breast cancer underwent [

resultsOf the lesions examined, 14/22 (64%) were ductal cancers, grade 2 or 3 (19/22; 86%), with 17/22 (77%) HER2-negative. [

conclusionHypoxia measured by [ KEY POINTS: • Hypoxia, measured by [

Indexed as

Breast NeoplasmsFemaleHumansHypoxiaHypoxia-Inducible Factor 1, alpha SubunitImmunohistochemistryMagnetic Resonance ImagingMisonidazolePositron-Emission TomographyfluoromisonidazoleHypoxia-Inducible Factor 1, alpha SubunitMisonidazoleBreast cancerCarbonic anhydrase IXHypoxiaMicrovessel densityPET/MRI

Identifiers

PMID37166494
PMCPMC10415421
OpenAlexW4376131240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.