ArticlePediatric transplantation2023
Imaging fibrosis in pediatric kidney transplantation: A pilot study.
Article in Pediatric transplantation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 13 citations in OpenAlex.
- Advanced MRI methods for children and young adults with autosomal recessive polycystic kidney disease (ARPKD) to support future multi-center clinical trials.Pediatric radiology · 2026Review
- Pediatric functional kidney MRI: advancements, challenges, and the value of quantitative multiparametric imaging.Pediatric radiology · 2026Article
- Quantitative MRI of pediatric chronic kidney disease and renal fibrosis: potential non-invasive clinical biomarkers.Pediatric radiology · 2026Review
- Magnetic resonance elastography of the pediatric kidney: technical considerations and emerging clinical applications.Pediatric radiology · 2026Review
- Summary from the 2025 International Society for Magnetic Resonance in Medicine workshop on body MRI: Unsolved problems and unmet needs.Magnetic resonance in medicine · 2026Review
- Detecting early kidney allograft fibrosis with multi-b-value spectral diffusion MRI.Scientific reports · 2025Article
- Association of In Vivo Kidney Stiffness Measured by Multifrequency MR Elastography and Long-Term Renal Function in Transplant Recipients and Living Donors.Journal of magnetic resonance imaging : JMRI · 2025Article
- Diffusion Tensor Imaging (DTI) as a Non-Invasive Tool for Assessing Pediatric Kidney Transplants: A Feasibility Study.Pediatric transplantation · 2025Article
- Spleen stiffness in a healthy pediatric population undergoing liver magnetic resonance elastography.Pediatric radiology · 2025Article
- Renal Ultrasonography in Children: Principles and Emerging Techniques.Current treatment options in pediatrics · 2024Article
- Advancements in Elastography for Evaluating Fibrosis in Renal Transplants: Current Perspectives.Biomedicines · 2024Review
- Magnetic resonance elastography resolving all gross anatomical segments of the kidney during controlled hydration.Frontiers in physiology · 2024Article
- Predicting Adverse Outcomes in Kidney Transplant Recipients Using an Interpretable Model Based on Shear-Wave Elastography.Kidney diseases (Basel, Switzerland)Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
backgroundNoninvasive alternatives to biopsy for assessment of interstitial fibrosis and tubular atrophy (IFTA), the major determinant of kidney transplant failure, remain profoundly limited. Elastography is a noninvasive technique that propagates shear waves across tissues to measure their stiffness. We aimed to test utility of elastography for early detection of IFTA in pediatric kidney allografts.
methodsWe compared ultrasound (USE) and MR elastography (MRE) stiffness measurements, performed on pediatric transplant recipients referred for clinically indicated biopsies, and healthy controls.
resultsTen transplant recipients (median age 16 years) and eight controls (median age 16.5 years) were enrolled. Three transplant recipients had "stable" allografts and seven had Banff Grade 1 IFTA. Median time from transplantation to biopsy was 12 months. Mean estimated glomerular filtration rate was 61.5 mL/min/1.73m
conclusionElastography shows potential for detection of low-grade IFTA in allografts although a larger sample is imperative for clinical validation.
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