Evidence map›Paper›PMID 37165688›Full record

SynthesisTherapeutic advances in respiratory disease

The effects of upper limb exercise training on upper limb muscle strength in people with chronic obstructive pulmonary disease: a systematic review and meta-analysis of randomized controlled trials.

Christos Karagiannis, Christos Savva, Vasileios Korakakis, George Ploutarchou, Tonia Adamide, Andreas Georgiou, Theodoros Xanthos

Open access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Therapeutic advances in respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Christos KaragiannisDepartment of Health Sciences, School of Sciences, European University Cyprus, 6, Diogenous Street, 2404 Engomi, P.O. Box: 22006, 1516 Nicosia, Cyprus.ORCID 0000-0001-5923-7721
Christos SavvaDepartment of Health Sciences, School of Sciences, European University of Cyprus, Nicosia, Cyprus.
Vasileios KorakakisDepartment of Population Health Sciences, School of Life Course & Population Sciences, King's College London, London, UK.
George PloutarchouDepartment of Health Sciences, School of Sciences, European University of Cyprus, Nicosia, Cyprus.
Tonia AdamideRespiratory Clinic, Nicosia General Hospital, Nicosia, Cyprus.
Andreas GeorgiouPrivate Doctor, Nicosia, Cyprus.
Theodoros XanthosSchool of Health and Care Sciences, University of West Attica, Athens, Greece.
European University Cyprus · CYKing's College London · GBNicosia General Hospital · CYUniversity of West Attica · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUpper limb (UL) muscle dysfunction is a common extrapulmonary manifestation of chronic obstructive pulmonary disease (COPD). UL muscle dysfunction is associated with muscle weakness, dyspnea, and exercise intolerance. Although upper limb exercise training (ULET) is typically incorporated in pulmonary rehabilitation programs, its effects on UL muscle strength remains unclear.

objectivesThe purpose of this systematic review was to investigate the effectiveness of ULET, in UL muscle strength of people with COPD.

designThis is systematic review and meta-analysis study. DATA SOURCES AND

methodsPreferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) Protocols 2020 guidelines were used for this study. PubMed, Cochrane, CINAHL Plus and SPORTDiscus and clinicaltrials.gov registry were searched from inception to July 2022. Included studies were randomized controlled trials, assessing the effectiveness in muscle strength of ULET, compared with other types of upper or lower limb exercise or no exercise. The quality and risk of bias were assessed using the Physiotherapy Evidence Database (PEDro) scale and certainty of evidence with the Grading of Recommendations, Assessment, Development, and Evaluations approach. Treatment effects of ULET were calculated using standardized mean differences and 95% confidence intervals.

resultsTwenty-four studies, with a total sample of 882 patients, were included. Most studies were of moderate quality and high risk of bias. Very low to low certainty evidence indicates a significant difference in UL muscle strength in favor of resistance ULET, compared with lower limb exercise alone or no exercise. No significant differences were found in different types of ULET comparisons.

conclusionThe results of this review showed that resistance ULET could improve UL muscle strength in people with COPD. Most studies, however, were of moderate quality and high risk of bias. Further studies with larger sample sizes, better methodological quality, and standardized training protocols are needed to confirm these findings.

Indexed as

Pulmonary Disease, Chronic ObstructiveQuality of LifeExerciseHumansMuscle StrengthPhysical Therapy ModalitiesRandomized Controlled Trials as TopicUpper Extremitychronic obstructive pulmonary diseasemeta-analysismuscle strengthsystematic reviewupper limbs

Identifiers

PMID37165688
PMCPMC10184263
OpenAlexW4376132274

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.