Evidence map›Paper›PMID 37165671›Full record

ArticleEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2023

Atrial substrate characterization based on bipolar voltage electrograms acquired with multipolar, focal and mini-electrode catheters.

Sven Knecht, Vincent Schlageter, Patrick Badertscher, Philipp Krisai, Florian Jousset, Thomas Küffer, Antonio Madaffari, Beat Schaer, Stefan Osswald, Christian Sticherling and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. An optimal output and electrode configuration for evaluating tissue transmurality - a preclinical study.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Article
  2. Article
  3. Observational
  4. 'Icosa-' instead of 'duodeca-': the meaning of words matters.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Sven KnechtDepartment of Cardiology, University Hospital Basel, University of Basel, Petersgraben 4, 4031 Basel, Switzerland.ORCID 0000-0001-7122-021X
Vincent SchlageterDepartment of Cardiology, University Hospital Basel, University of Basel, Petersgraben 4, 4031 Basel, Switzerland.ORCID 0000-0001-6305-5103
Patrick BadertscherDepartment of Cardiology, University Hospital Basel, University of Basel, Petersgraben 4, 4031 Basel, Switzerland.ORCID 0000-0001-9751-0557
Philipp KrisaiDepartment of Cardiology, University Hospital Basel, University of Basel, Petersgraben 4, 4031 Basel, Switzerland.ORCID 0000-0002-4367-2363
Florian JoussetBoston Scientific, Rhythm Management, Solothurn, Switzerland.ORCID 0000-0002-0807-4827
Thomas KüfferDepartment of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID 0000-0003-3553-4945
Antonio MadaffariDepartment of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID 0000-0001-8364-3279
Beat SchaerDepartment of Cardiology, University Hospital Basel, University of Basel, Petersgraben 4, 4031 Basel, Switzerland.ORCID 0000-0003-1768-1968
Stefan OsswaldDepartment of Cardiology, University Hospital Basel, University of Basel, Petersgraben 4, 4031 Basel, Switzerland.ORCID 0000-0002-9240-6731
Christian SticherlingDepartment of Cardiology, University Hospital Basel, University of Basel, Petersgraben 4, 4031 Basel, Switzerland.ORCID 0000-0001-8428-7050
Michael KühneDepartment of Cardiology, University Hospital Basel, University of Basel, Petersgraben 4, 4031 Basel, Switzerland.ORCID 0000-0002-2937-3711
University of Basel · CHUniversity of Bern · CHSchweizerische Ärztegesellschaft für Psycholytische Therapie · CH

Funding

Boston Scientific ISRRM10392
6 · The paper itself

Abstract

backgroundBipolar voltage (BV) electrograms for left atrial (LA) substrate characterization depend on catheter design and electrode configuration.

aimsThe aim of the study was to investigate the relationship between the BV amplitude (BVA) using four catheters with different electrode design and to identify their specific LA cutoffs for scar and healthy tissue. METHODS AND

resultsConsecutive high-resolution electroanatomic mapping was performed using a multipolar-minielectrode Orion catheter (Orion-map), a duo-decapolar circular mapping catheter (Lasso-map), and an irrigated focal ablation catheter with minielectrodes (Mifi-map). Virtual remapping using the Mifi-map was performed with a 4.5 mm tip-size electrode configuration (Nav-map). BVAs were compared in voxels of 3 × 3 × 3 mm3. The equivalent BVA cutoff for every catheter was calculated for established reference cutoff values of 0.1, 0.2, 0.5, 1.0, and 1.5 mV. We analyzed 25 patients (72% men, age 68 ± 15 years). For scar tissue, a 0.5 mV cutoff using the Nav corresponds to a lower cutoff of 0.35 mV for the Orion and of 0.48 mV for the Lasso. Accordingly, a 0.2 mV cutoff corresponds to a cutoff of 0.09 mV for the Orion and of 0.14 mV for the Lasso. For healthy tissue cutoff at 1.5 mV, a larger BVA cutoff for the small electrodes of the Orion and the Lasso was determined of 1.68 and 2.21 mV, respectively.

conclusionWhen measuring LA BVA, significant differences were seen between focal, multielectrode, and minielectrode catheters. Adapted cutoffs for scar and healthy tissue are required for different catheters.

Indexed as

Atrial substrateBipolar voltage amplitudeCatheterElectrode

Identifiers

PMID37165671
PMCPMC10228606
OpenAlexW4376131305

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.