Evidence map›Paper›PMID 37165289›Full record

Observational studyTranslational stroke research2024

Long-Term Follow-Up of Cerebral Aneurysms Completely Occluded at 6 Months After Intervention with the Woven EndoBridge (WEB) Device: a Retrospective Multicenter Observational Study.

Kareem El Naamani, Panagiotis Mastorakos, Nimer Adeeb, Mathews Lan, James Castiglione, Omaditya Khanna, Jose Danilo Bengzon Diestro, Rachel M McLellan, Mahmoud Dibas, Justin E Vranic and 44 more

Abstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Translational stroke research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

54 authors at 20 institutions in 8 countries.

Kareem El NaamaniDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Panagiotis MastorakosDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Nimer AdeebDepartement of Neurosurgery and Neurointerventional Surgery, Louisiana State University, Shreveport, LA, USA.
Mathews LanDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
James CastiglioneDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Omaditya KhannaDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Jose Danilo Bengzon DiestroNeurovascular Centre, Departments of Medical Imaging & Neurosurgery, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Rachel M McLellanNeuroendovascular Program, Massachusetts General Hospital & Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Mahmoud DibasNeurovascular Centre, Departments of Medical Imaging & Neurosurgery, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Justin E VranicNeuroendovascular Program, Massachusetts General Hospital & Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Assala AslanDepartement of Neurosurgery and Neurointerventional Surgery, Louisiana State University, Shreveport, LA, USA.
Hugo H Cuellar-SaenzDepartement of Neurosurgery and Neurointerventional Surgery, Louisiana State University, Shreveport, LA, USA.
Adrien GuenegoService de Neuroradiologie Interventionnelle, Hôpital Universitaire Erasme, Brussels, Belgium.
Joseph CarnevaleNeurosurgery & Interventional Neuroradiology, Weill Cornell School of Medicine, New York Presbyterian Hospital, New York, NY, USA.
Guillaume SaliouService de Radiodiagnostic et Radiologie Interventionnelle, Centre Hospitalier Vaudois de Lausanne, Lausanne, Switzerland.
Christian UlfertSektion Vaskuläre und Interventionelle Neuroradiologie, Universitätsklinikum Heidelberg, Heidelberg, Germany.
Markus MöhlenbruchSektion Vaskuläre und Interventionelle Neuroradiologie, Universitätsklinikum Heidelberg, Heidelberg, Germany.
Paul M ForemanNeurosurgery Department, Orlando Health Neuroscience and Rehabilitation Institute, Orlando, FL, USA.
Jay A VachhaniNeurosurgery Department, Orlando Health Neuroscience and Rehabilitation Institute, Orlando, FL, USA.
Muhammad U HafeezDepartment of Neurosurgery, UTMB and Baylor School of Medicine, Houston, TX, USA.
Muhammad WaqasDepartment of Neurosurgery, State University of New York at Buffalo, Buffalo, NY, USA.
Vincent M TutinoDepartment of Neurosurgery, State University of New York at Buffalo, Buffalo, NY, USA.
James D RabinovNeuroendovascular Program, Massachusetts General Hospital & Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Yifan RenInterventional Radiology and Neurointerventional Services, Department of Radiology, Austin Health, Melbourne, VIC, Australia.
Caterina MichelozziInterventistica Neurovascolare, Ospedale Niguarda Cà Granda, Milan, Italy.
Julian SpearsNeurovascular Centre, Departments of Medical Imaging & Neurosurgery, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Pietro PanniInterventional Neuroradiology and Neurosurgery, San Raffaele University Hospital, Milan, Italy.
Christoph J GriessenauerDepartment of Neurosurgery, Christian Doppler University Hospital, Paracelsus Medical University Salzburg, Salzburg, Austria.
Hamed AsadiInterventional Radiology and Neurointerventional Services, Department of Radiology, Austin Health, Melbourne, VIC, Australia.
Robert W RegenhardtNeuroendovascular Program, Massachusetts General Hospital & Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Christopher J StapletonNeuroendovascular Program, Massachusetts General Hospital & Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Sherief GhozyNeuroendovascular Program, Massachusetts General Hospital & Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Adnan SiddiquiDepartment of Neurosurgery, State University of New York at Buffalo, Buffalo, NY, USA.
Nirav J PatelNeuroendovascular Program, Massachusetts General Hospital & Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Peter KanDepartment of Neurosurgery, UTMB and Baylor School of Medicine, Houston, TX, USA.
Srikanth BodduNeurosurgery & Interventional Neuroradiology, Weill Cornell School of Medicine, New York Presbyterian Hospital, New York, NY, USA.
Jared KnopmanNeurosurgery & Interventional Neuroradiology, Weill Cornell School of Medicine, New York Presbyterian Hospital, New York, NY, USA.
Mohammad A Aziz-SultanNeuroendovascular Program, Massachusetts General Hospital & Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Mario ZanatyDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Ritam GhoshDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Rawad AbbasDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Abdelaziz AmllayDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Stavropoula I TjoumakarisDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Michael R GoochDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Nicole M CancelliereNeurovascular Centre, Departments of Medical Imaging & Neurosurgery, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Nabeel A HerialDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Robert H RosenwasserDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Hekmat ZarzourDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Richard F SchmidtDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Vitor Mendes PereiraNeurovascular Centre, Departments of Medical Imaging & Neurosurgery, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Aman B PatelNeuroendovascular Program, Massachusetts General Hospital & Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Pascal JabbourDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Adam A DmytriwNeurovascular Centre, Departments of Medical Imaging & Neurosurgery, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada. admytriw@mgh.harvard.edu.
WorldWideWEB Consortium
Thomas Jefferson University Hospital · USNeurological Surgery · USBrigham and Women's Hospital · USLouisiana State University in Shreveport · USMassachusetts General Hospital · USUniversity at Buffalo, State University of New York · USUniversity of Toronto · CAAustin Health · AUBaylor School · USHarvard University · USNewYork–Presbyterian Hospital · USOrlando Health · USSt. Michael's Hospital · CAAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITCornell University · USErasmus Hospital · BEHeidelberg University · DEParacelsus Medical University · ATSan Raffaele University of Rome · ITUniversity Hospital Heidelberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Woven EndoBridge (WEB) device has been widely used to treat intracranial wide neck bifurcation aneurysms. Initial studies have demonstrated that approximately 90% of patients have same or improved long-term aneurysm occlusion after the initial 6-month follow up. The aim of this study is to assess the long-term follow-up in aneurysms that have achieved complete occlusion at 6 months. We also compared the predictive value of different imaging modalities used. This is an analysis of a prospectively maintained database across 13 academic institutions. We included patients with previously untreated cerebral aneurysms embolized using the WEB device who achieved complete occlusion at first follow-up and had available long-term follow-up. A total of 95 patients with a mean age of 61.6 ± 11.9 years were studied. The mean neck diameter and height were 3.9 ± 1.3 mm and 6.0 ± 1.8 mm, respectively. The mean time to first and last follow-up was 5.4 ± 1.8 and 14.1 ± 12.9 months, respectively. Out of all the aneurysms that were completely occluded at 6 months, 84 (90.3%) showed complete occlusion at the final follow-up, and 11(11.5%) patients did not achieve complete occlusion. The positive predictive value (PPV) of complete occlusion at first follow was 88.4%. Importantly, this did not differ between digital subtraction angiography (DSA), magnetic resonance angiography (MRA), or computed tomography angiography (CTA). This study underlines the importance of repeat imaging in patients treated with the WEB device even if complete occlusion is achieved short term. Follow-up can be performed using DSA, MRA or CTA with no difference in positive predictive value.

Indexed as

Intracranial AneurysmAgedEmbolization, TherapeuticEndovascular ProceduresFemaleFollow-Up StudiesHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeAneurysmImagingObliterationPositive predictive valueWEB device

Identifiers

PMID37165289
OpenAlexW4376131767

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.