ArticleNature metabolism2023
Human metabolome variation along the upper intestinal tract.
Article in Nature metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
82 citing papers in PubMed, 131 citations in OpenAlex.
- Prebiotic Administration to Chronic Kidney Disease Patients Modifies Their Fecal Microbiome and Host Metabolism.Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation · 2026Trial
- Untargeted and semi-targeted metabolomics approach for profiling small intestinal and fecal metabolome using high-resolution mass spectrometry.Metabolomics : Official journal of the Metabolomic Society · 2025Trial
- The Impact of Milk on Gut Permeability, Fecal 16S rRNA Gene Microbiota Profiling, and Fecal Metabolomics in Children with Moderate Malnutrition in Sierra Leone: A Double-Blind, Randomized Controlled Trial.The American journal of clinical nutrition · 2024Trial
- Regional organization of nutrient absorption across the small intestine.Nature reviews. Gastroenterology & hepatology · 2026Review
- Effects of Bioactive Microalgal Pigment Intake on Metabolic Parameters, Cecal Distribution and Short-Chain Fatty Acids in a Diabetic Rat Model.Life (Basel, Switzerland) · 2026Article
- From Diet to Dysbiosis: The Microbiome's Relationship to Eosinophilic Esophagitis.Current gastroenterology reports · 2026Review
- Microbial single-cell transcriptomics links gut microbiota functional states to metabolic changes in male mice.Nature communications · 2026Article
- Multi-region sampling of the human small intestine using an ingestible device.medRxiv : the preprint server for health sciences · 2026Article
- A lipidomics roadmap: from basic research to societal challenges.Nature communications · 2026Review
- Comparison of fecal and plasma metabolite correlations following nutrition or exercise interventions.Metabolomics : Official journal of the Metabolomic Society · 2026Article
- Microbiome-produced nicotinic acid controls colon regional identity and injury susceptibility.Cell · 2026Article
- Restriction of IgA secretion in gut plasma cells is driven by a tissue-specific glycolytic program.Journal of immunology (Baltimore, Md. : 1950) · 2026Article
- Ingestible active capsule for gastrointestinal microbiome sampling.Biomedical microdevices · 2026Article
- Gut microbiome modulation by cricket, pea, and whey protein using the SHIME in vitro simulator.NPJ science of food · 2026Article
- Developmental plasticity enables an intestinal tapeworm to adapt to dietary stress.Nature communications · 2026Article
- MS/MS Mass Spectrometry Filtering Tree for Bile Acid Regio- and Stereoisomer Annotation.Analytical chemistry · 2026Article
- Small intestine is not colon: a newGut microbes · 2025Article
- Chemotherapy-driven intestinal dysbiosis and indole-3-propionic acid rewire myelopoiesis to promote a metastasis-refractory state.Nature communications · 2025Article
- Short-Term Alcohol Consumption Is Sufficient to Disrupt Microbial Communities and the Intestinal and Circulating Metabolites in a Non-Human Primate Model.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Article
- Spatial Multi-Omics Analysis of the Qianqiu Goat Gut Microbiome and Metabolome.International journal of molecular sciences · 2025Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
Most processing of the human diet occurs in the small intestine. Metabolites in the small intestine originate from host secretions, plus the ingested exposome
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.