ArticleScientific reports2023
Assessment of the incremental prognostic value from the modified frailty index-5 in complete traumatic cervical spinal cord injury.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Evidence-based recommendations for the rehabilitation and management of the ageing population with spinal cord injury: a systematic review of clinical practice guidelines.European journal of physical and rehabilitation medicine · 2024Pooled it
- Temporal trends in major in-hospital and immobility-related complications following traumatic spinal cord injury: a retrospective cohort study.Journal of spine surgery (Hong Kong) · 2026Article
- Traumatic spinal cord injury in the elderly: predictors for mortality and functional outcomes.Journal of spine surgery (Hong Kong) · 2025Article
- Predictive ability of frailty scores in surgically managed patients with traumatic spinal injuries: a TQIP analysis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025Article
- Factors influencing withdrawal of life-supporting treatment in cervical spinal cord injury: a large multicenter observational cohort study.Critical care (London, England) · 2023Observational
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Frailty, as measured by the modified frailty index-5 (mFI-5), and older age are associated with increased mortality in the setting of spinal cord injury (SCI). However, there is limited evidence demonstrating an incremental prognostic value derived from patient mFI-5. We conducted a retrospective cohort study to evaluate in-hospital mortality among adult complete cervical SCI patients at participating centers of the Trauma Quality Improvement Program from 2010 to 2018. Logistic regression was used to model in-hospital mortality, and the area under the receiver operating characteristic curve (AUROC) of regression models with age, mFI-5, or age with mFI-5 was used to compare the prognostic value of each model. 4733 patients were eligible. We found that both age (80 y versus 60 y: OR 3.59 95% CI [2.82 4.56], P < 0.001) and mFI-5 (score ≥ 2 versus < 2: OR 1.53 95% CI [1.19 1.97], P < 0.001) had statistically significant associations with in-hospital mortality. There was no significant difference in the AUROC of a model including age and mFI-5 when compared to a model including age without mFI-5 (95% CI Δ AUROC [- 8.72 × 10
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