Evidence map›Paper›PMID 37164940›Full record

ArticleNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2023

Management of antineutrophil cytoplasmic antibody-associated vasculitis with glomerulonephritis as proposed by the ACR 2021, EULAR 2022 and KDIGO 2021 guidelines/recommendations.

Marta Casal Moura, Philipp Gauckler, Hans-Joachim Anders, Annette Bruchfeld, Gema M Fernandez-Juarez, Jürgen Floege, Eleni Frangou, Dimitrios Goumenos, Marten Segelmark, Kultigin Turkmen and 7 more

Open access · hybridAbstract read
In one paragraph

Article in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Long-Term Outcomes of Rituximab-Treated Adult Patients with Podocytopathies.Journal of the American Society of Nephrology : JASN · 2025
    Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 16 institutions in 12 countries.

Marta Casal MouraDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.
Philipp GaucklerDepartment of Internal Medicine IV (Nephrology and Hypertension), Medical University Innsbruck, Innsbruck, Austria.
Hans-Joachim AndersDepartment of Internal Medicine IV, Hospital of the Ludwig Maximilians University, Munich, Germany.
Annette BruchfeldDepartment of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.
Gema M Fernandez-JuarezDepartment of Nephrology, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain.
Jürgen FloegeDivision of Nephrology, RWTH Aachen University Hospital, Aachen, Germany.
Eleni FrangouDepartment of Nephrology, Limassol General Hospital, SHSO, Cyprus; Medical School, University of Nicosia, Nicosia, Cyprus.
Dimitrios GoumenosDepartment of Nephrology and Renal Transplantation, Patras University Hospital, Patras, Greece.
Marten SegelmarkDivision of Nephrology, Department of Clinical Sciences Lund, Lund University and Skane University Hospital, Lund, Sweden.
Kultigin TurkmenDivision of Nephrology, Department of Internal Medicine, Necmettin Erbakan University, Konya, Turkey.
Cees van KootenDivision of Nephrology and Transplant Medicine, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands.
Vladimir TesarDepartment of Nephrology, First Faculty of Medicine and General University Hospital, Charles University, Prague, Czechia.
Duvuru GeethaDivision of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.
Fernando C FervenzaDivision of Nephrology and Hypertension, Department of Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.
David R W JayneDepartment of Medicine, University of Cambridge, Cambridge, United Kingdom.
Kate I StevensDivision of Nephrology and Transplantation, Queen Elizabeth University Hospital, Glasgow, United Kingdom.
Andreas KronbichlerDepartment of Medicine, University of Cambridge, Cambridge, United Kingdom.
University of Cambridge · GBCharles University · CZGeneral University Hospital of Patras · GRHospital Universitario La Paz · ESInnsbruck Medical University · ATJohns Hopkins Medicine · USKarolinska University Hospital · SELeiden University Medical Center · NLLimassol General Hospital · CYLudwig-Maximilians-Universität München · DELund University · SEMayo Clinic · USNecmettin Erbakan University · TRQueen Elizabeth University Hospital · GBUniversidade do Porto · PTUniversitätsklinikum Aachen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Updated guidelines on the management of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) were released in 2021 by the American College of Rheumatology jointly with the Vasculitis Foundation and, subsequently, in 2022 by the European Alliance of Associations for Rheumatology. In addition, in 2021, the Kidney Disease: Improving Global Outcomes had released updated recommendations on the treatment of AAV with glomerulonephritis (AAV-GN). Kidney involvement is particularly relevant in microscopic polyangiitis and granulomatosis with polyangiitis, but is less frequent in eosinophilic granulomatosis with polyangiitis. The management of AAV-GN has been a focus for drug development and change over the past 10 years. Avoidance of progression to end-stage kidney disease (ESKD) or kidney failure is one of the main unmet needs in the management of AAV, with ESKD having a major impact on morbidity, health costs and mortality risk. Relevant changes in AAV-GN management are related to remission-induction treatment of patients with severe kidney disease, the use of glucocorticoids and avacopan, and remission-maintenance treatment. All the documents provide guidance in accordance with the evidence-based standard of care available at the time of their release. With our work we aim to (i) show the progress made and identify the differences between guidelines and recommendations, (ii) discuss the supporting rationale for those, and (iii) identify gaps in knowledge that could benefit from additional research and should be revised in subsequent updates.

Indexed as

Anti-Neutrophil Cytoplasmic Antibody-Associated VasculitisChurg-Strauss SyndromeGlomerulonephritisGranulomatosis with PolyangiitisKidney Failure, ChronicMicroscopic PolyangiitisAntibodies, Antineutrophil CytoplasmicHumansAntibodies, Antineutrophil CytoplasmicANCA-associated vasculitisglomerulonephritisgranulomatosis with polyangiitisguidelinesmicroscopic polyangiitis

Identifiers

PMID37164940
PMCPMC10615627
OpenAlexW4376132685

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.