Evidence map›Paper›PMID 37164915›Full record

ArticleZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2023

Effects of microRNA-21 on endothelial-to-mesenchymal transition and its role in the pathogenesis of chronic obstructive pulmonary disease.

Yumei Liao, Zhengpeng Zeng, Jinwen Cai, Shenghua Sun, Lihua Xie

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yumei LiaoDepartment of Pulmonary and Critical Care Medicine, Third Xiangya Hospital, Central South University, Changsha 410013. 790450009@qq.com.
Zhengpeng ZengCenter of Health Management, Third Xiangya Hospital, Central South University, Changsha 410013, China.
Jinwen CaiDepartment of Pulmonary and Critical Care Medicine, Third Xiangya Hospital, Central South University, Changsha 410013.
Shenghua SunDepartment of Pulmonary and Critical Care Medicine, Third Xiangya Hospital, Central South University, Changsha 410013.
Lihua XieDepartment of Pulmonary and Critical Care Medicine, Third Xiangya Hospital, Central South University, Changsha 410013. xyelyhua@163.com.
Central South University · CN

Funding

the National Natural Science Foundation of China 82070048
6 · The paper itself

Abstract

objectivesChronic obstructive pulmonary disease (COPD) is a disease characterized by persistent airflow restriction. This study aims to explore whether there is endothelial-to-mesenchymal transition (EndMT) in COPD mice and to explore the relationship between microRNA-21 (miR-21) and EndMT.

methodsWe established the COPD and the

resultsCompared with the control group, the area of collagen fibril deposition was increased in the COPD group (

conclusionsThere is a EndMT process in cigarette smoke-induced COPD animal models.

Indexed as

MicroRNAsPulmonary Disease, Chronic ObstructiveAnimalsCadherinsCollagenEpithelial-Mesenchymal TransitionMiceCadherinsCollagenMicroRNAsMIRN21 microRNA, mousechronic obstructive pulmonary diseaseendothelial-to-mesenchymal transitionmiR-21vascular remodeling

Identifiers

PMID37164915
PMCPMC10930074
OpenAlexW4376133410

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.