Evidence map›Paper›PMID 37164781›Full record

ReviewEBioMedicine2023

Harmful algal bloom aerosols and human health.

Chris C Lim, Jeonggyo Yoon, Kelly Reynolds, Lynn B Gerald, Andrew P Ault, Seulkee Heo, Michelle L Bell

Open access · goldAbstract readReview
In one paragraph

Review in EBioMedicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
16.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 62 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Chris C LimZuckerman College of Public Health, The University of Arizona, Tucson, Arizona, USA. Electronic address: chrislim@arizona.edu.
Jeonggyo YoonZuckerman College of Public Health, The University of Arizona, Tucson, Arizona, USA.
Kelly ReynoldsZuckerman College of Public Health, The University of Arizona, Tucson, Arizona, USA.
Lynn B GeraldPopulation Health Sciences Program, Office of the Vice Chancellor for Health Affairs, University of Illinois Chicago, Chicago, Illinois, USA.
Andrew P AultDepartment of Chemistry, University of Michigan, Ann Arbor, Michigan, USA.
Seulkee HeoSchool of the Environment, Yale University, New Haven, Connecticut, USA.
Michelle L BellSchool of the Environment, Yale University, New Haven, Connecticut, USA.
University of Arizona · USYale University · USChicago Department of Public Health · USUniversity of Michigan · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Environmental Health Disparities in an Older PopulationR01MD012769 · NIMHD · YALE UNIVERSITY · PI BELL, MICHELLE L · 2017 to 2021
$3.9M
NCATS NIH HHS UL1 TR001863NIMHD NIH HHS R01 MD012769
6 · The paper itself

Abstract

Harmful algal blooms (HABs) are increasing across many locations globally. Toxins from HABs can be incorporated into aerosols and transported inland, where subsequent exposure and inhalation can induce adverse health effects. However, the relationship between HAB aerosols and health outcomes remains unclear despite the potential for population-level exposures. In this review, we synthesized the current state of knowledge and identified evidence gaps in the relationship between HAB aerosols and human health. Aerosols from Karenia brevis, Ostreopsis sp., and cyanobacteria were linked with respiratory outcomes. However, most works did not directly measure aerosol or toxin concentrations and instead relied on proxy metrics of exposure, such as cell concentrations in nearby waterbodies. Furthermore, the number of studies with epidemiological designs was limited. Significant uncertainties remain regarding the health effects of other HAB species; threshold dose and the dose-response relationship; effects of concurrent exposures to mixtures of toxins and other aerosol sources, such as microplastics and metals; the impact of long-term exposures; and disparities in exposures and associated health effects across potentially vulnerable subpopulations. Additional studies employing multifaceted exposure assessment methods and leveraging large health databases could address such gaps and improve our understanding of the public health burden of HABs.

Indexed as

Harmful Algal BloomPlasticsAerosolsHumansAerosolsPlasticsAerosolsClimate changeHarmful algal bloomsHuman health

Identifiers

PMID37164781
PMCPMC10363441
OpenAlexW4376133120

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.