Evidence map›Paper›PMID 37164671›Full record

ArticleInternal medicine (Tokyo, Japan)2023

Cutaneous Metastasis of Transverse Colon Cancer with an Aberrant Pattern of CK7/CK20/CDX2 and High Microsatellite Instability.

Moeko Omiya, Takaaki Murata, Akira Sawaki, Shinichi Teshima, Jun Kawachi

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Moeko OmiyaDepartment of General Internal Medicine, Shonan Kamakura General Hospital, Japan.
Takaaki MurataDepartment of Surgery, Shonan Kamakura General Hospital, Japan.
Akira SawakiDepartment of Medical Oncology, Shonan Kamakura General Hospital, Japan.
Shinichi TeshimaDepartment of Pathology, Shonan Kamakura General Hospital, Japan.
Jun KawachiDepartment of Surgery, Shonan Kamakura General Hospital, Japan.
Shonan Kamakura General Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 79-year-old woman was diagnosed with transverse colon cancer, moderately differentiated adenocarcinoma. She underwent surgery and postoperative adjuvant chemotherapy. At 80 years old, the patient exhibited changes in skin tone at the chest and abdomen with CK7+/CK20-/CDX2- immunostaining that was later identified as poorly differentiated adenocarcinoma. The diagnosis was cancer of unknown primary origin. The patient passed away three months after the detection of the skin lesion. Autopsy revealed recurrence at the transverse colon, multiple organ metastases, a similar postmortem immunostaining pattern, and high-frequency microsatellite instability (MSI-high). We herein report this case of CK7+/CK20-/CDX2- and MSI-high transverse colon cancer showing cutaneous metastasis.

Indexed as

AdenocarcinomaColonic NeoplasmsColon, TransverseSkin NeoplasmsAgedAged, 80 and overBiomarkers, TumorCDX2 Transcription FactorFemaleHomeodomain ProteinsHumansKeratin-20Microsatellite InstabilityBiomarkers, TumorCDX2 protein, humanCDX2 Transcription FactorHomeodomain ProteinsKeratin-20CDX2-CK7+/CK20-colorectal cancercutaneous metastasismicrosatellite instability

Identifiers

PMID37164671
PMCPMC10781542
OpenAlexW4376132549

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.