ArticleOccupational and environmental medicine2023
Radon and lung cancer in the pooled uranium miners analysis (PUMA): highly exposed early miners and all miners.
Article in Occupational and environmental medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Indoor Radon Exposure Among Schoolchildren: A Systematic Review of Risk Factors.International journal of environmental research and public health · 2026Pooled it
- Radon exposure and potential health effects other than lung cancer: a systematic review and meta-analysis.Frontiers in public health · 2024Pooled it
- Radon-Induced Radiation Biomarkers: A Scoping Review from Exposure Dosimetry to Early Biological Effects on the Lung.International journal of molecular sciences · 2026Article
- Radon diagnostics using low-cost continuous monitors and air exchange rate measurement - a case study in a residential building.Radiation and environmental biophysics · 2026Article
- Extracellular vesicle proteomic expression is influenced by mining tenure in former uranium miners.Environmental research · 2025Article
- Uranium mining and lung cancer: a legacy of the nuclear age.Carcinogenesis · 2025Review
- Exposure to radon progeny and cancer mortality, excluding lung cancer, in the cohort of Newfoundland Fluorspar Miners between 1950 and 2016.Radiation and environmental biophysics · 2025Article
- Updated cancer mortality among uranium miners on the Colorado Plateau: interactions of radon exposure with smoking and temporal factors.Occupational and environmental medicine · 2025Article
- Inverse probability weighting to estimate impacts of hypothetical occupational limits on radon exposure to reduce lung cancer.American journal of epidemiology · 2025Article
- Epidemiological profile and determinants of whole blood heavy metal levels in occupationally exposed populations: a cross-sectional study in Hunan Province, China.Frontiers in public health · 2025Article
- On the informative value of community-based indoor radon values in relation to lung cancer.Cancer medicine · 2024Article
- A Historical Survey of Key Epidemiological Studies of Ionizing Radiation Exposure.Radiation research · 2024Review
- Lifetime excess absolute risk for lung cancer due to exposure to radon: results of the pooled uranium miners cohort study PUMA.Radiation and environmental biophysics · 2024Article
- Updated risk models for lung cancer due to radon exposure in the German Wismut cohort of uranium miners, 1946-2018.Radiation and environmental biophysics · 2023Article
- Inverse dose protraction effects of high-LET radiation: Evidence and significance.Mutation research. Reviews in mutation researchReview
Corrections and comments
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Authors and funding
14 authors at 10 institutions in 6 countries.
Funding
Abstract
objectivesRadon is a ubiquitous occupational and environmental lung carcinogen. We aim to quantify the association between radon progeny and lung cancer mortality in the largest and most up-to-date pooled study of uranium miners.
methodsThe pooled uranium miners analysis combines 7 cohorts of male uranium miners with 7754 lung cancer deaths and 4.3 million person-years of follow-up. Vital status and lung cancer deaths were ascertained between 1946 and 2014. The association between cumulative radon exposure in working level months (WLM) and lung cancer was modelled as the excess relative rate (ERR) per 100 WLM using Poisson regression; variation in the association by temporal and exposure factors was examined. We also examined analyses restricted to miners first hired before 1960 and with <100 WLM cumulative exposure.
resultsIn a model that allows for variation by attained age, time since exposure and annual exposure rate, the ERR/100 WLM was 4.68 (95% CI 2.88 to 6.96) among miners who were less than 55 years of age and were exposed in the prior 5 to <15 years at annual exposure rates of <0.5 WL. This association decreased with older attained age, longer time since exposure and higher annual exposure rate. In analyses restricted to men first hired before 1960, we observed similar patterns of association but a slightly lower estimate of the ERR/100 WLM.
conclusionsThis new large, pooled study confirms and supports a linear exposure-response relationship between cumulative radon exposure and lung cancer mortality which is jointly modified by temporal and exposure factors.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.