ReviewAmerican journal of obstetrics and gynecology2023
Placental abruption at near-term and term gestations: pathophysiology, epidemiology, diagnosis, and management.
Review in American journal of obstetrics and gynecology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 1 synthesis or guideline pooled it, 83 citations in OpenAlex.
- Independent risk factors for placental abruption: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2025Pooled it
- Fetomaternal hemorrhage: pathogenesis, diagnosis, and clinical management.Journal of perinatology : official journal of the California Perinatal Association · 2026Review
- Gestational-Age Clustering of Recurrent Placental Abruption: A Multicenter Retrospective Descriptive Study.Journal of clinical medicine · 2026Article
- A New Severity Index for Placental Abruption Predicts Recurrence Risk in Future Pregnancies.Journal of clinical medicine · 2026Article
- A Retrospective Evaluation of Perinatal Outcomes in Pregnant Women With Isolated Gestational Proteinuria.Cureus · 2026Article
- Umbilical cord ulceration associated with placental abruption: a case report.BMC pregnancy and childbirth · 2026Article
- Association between small-for-gestational-age at birth and placental abruption in normotensive pregnancies: a retrospective cohort study.BMC pregnancy and childbirth · 2026Article
- Association of Maternal Cardiac Arrhythmias with Pregnancy Outcomes: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2026Review
- Cardiovascular Disease in Singleton Offspring Born of Pregnancies Complicated by Placental Abruption: A Population-Based Retrospective Cohort Study.Journal of the American Heart Association · 2026Article
- Identification of a DICER1 mutation in a preeclamptic patient with ruptured ovarian Sertoli-Leydig cell tumor and renal allograft failure under hemodialysis: a case report.BMC pregnancy and childbirth · 2026Article
- Placental Abruption, Preterm Delivery, and Cardiovascular Disease in Twin Offspring.Journal of the American Heart Association · 2026Article
- Placental Abruption and Perinatal Mortality: Abnormal Placentation and Spontaneous Abortion as Contributors to Left Truncation Bias.Paediatric and perinatal epidemiology · 2026Article
- Vertical versus transverse abdominal incision in placental abruption: a propensity score-matched study on the trade-off between speed and maternal-neonatal safety.Frontiers in medicine · 2026Article
- Conservative management leading to delivery of a twin pregnancy complicated by previable preterm premature rupture of membranes: a case report.AME case reports · 2026Article
- A Comprehensive Evidence-Based Review of Non-Pharmaceutical Interventions for Neonatal Pain.Journal of pain research · 2026Review
- Temporal trends in lupus pregnancy over four decades in a referral centre: pregnancy planning and hydroxychloroquine use are associated with improved outcomes.Rheumatology advances in practice · 2026Article
- Causal Effects of Common Pregnancy Complications on Neonatal Birth Weight: A Mendelian Randomization Study.International journal of women's health · 2026Article
- Article
- Early Adverse Perinatal Outcomes Among Women With Placental Abruption: A Multicenter Prospective Cohort Study in Uganda.Journal of pregnancy · 2026Observational
- Correlation Between Placental Calcification, Umbilical Artery Hemodynamic Parameters and Delivery Outcomes in Patients with Gestational Diabetes.International journal of women's health · 2026Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Placental abruption is the premature separation of the placenta from its uterine attachment before the delivery of a fetus. The clinical manifestations of abruption typically include vaginal bleeding and abdominal pain with a wide variety of abnormal fetal heart rate patterns. Clinical challenges arise when pregnant people with this condition present with profound vaginal bleeding, necessitating urgent delivery, especially when there is a concern for maternal and fetal compromise and coagulopathy. Abruption occurs in 0.6% to 1.2% of all pregnancies, with nearly half of abruption occurring at term gestations. An exposition of abruption at near-term (defined as the late preterm period from 34 0/7 to 36 6/7 weeks of gestation) and term (defined as ≥37 weeks of gestation) provides unique insights into its direct effects, as risks associated with preterm birth do not impact outcomes. Here, we explore the pathophysiology, epidemiology, and diagnosis of abruption. We discuss the interaction of chronic processes (decidual and uteroplacental vasculopathy) and acute processes (shearing forces applied to the abdomen) that underlie the pathophysiology. Risk factors for abruption and strengths of association are summarized. Sonographic findings of abruption and fetal heart rate tracings are presented. In addition, we propose a management algorithm for acute abruption that incorporates blood loss, vital signs, and urine output, among other factors. Lastly, we discuss blood component therapy, viscoelastic point-of-care testing, disseminated intravascular coagulopathy, and management of abruption complicated by fetal death. The review seeks to provide comprehensive, clinically focused guidance during a gestational age range when neonatal outcomes can often be favorable if rapid and evidence-based care is optimized.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.