Evidence map›Paper›PMID 37164471›Full record

Observational studyBMJ open2023

Prevalence, antimicrobial susceptibility pattern and multidrug resistance of methicillin-resistant

Prashant Adhikari, Deepak Basyal, Junu Richhinbung Rai, Laxman Bharati, Arjun Budthapa, Kul Prasad Gharti, Shiv Kumar Sah

Abstract readObservational Study
In one paragraph

Observational study in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Global prevalence of macrolide-resistantFrontiers in microbiology · 2025
    Pooled it
  2. Article
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  4. Article
  5. Article
  6. Enterotoxin and biofilm producing Staphylococcus aureus and MRSA isolates from animal source foods sold in Assam.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  7. Article
  8. Antimicrobial resistance and biofilm-forming ability inVeterinary and animal science · 2025
    Article
  9. Systematic review and meta-analysis ofOne health (Amsterdam, Netherlands) · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Iranian journal of microbiology · 2025
    Article
  16. Nasal carriage rate and multiple antimicrobial resistance indices ofAfrican journal of laboratory medicine · 2025
    Article
  17. Article
  18. Article
  19. Aerosol-Mediated Spread of Antibiotic Resistance Genes: Biomonitoring Indoor and Outdoor Environments.International journal of environmental research and public health · 2024
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Prashant AdhikariDepartment of Pharmacy, Maharajgunj Medical Campus (MMC), Institute of Medicine (IOM), Tribhuvan University, Kathmandu, Bagmati, Nepal.
Deepak BasyalDepartment of Pharmacy, Maharajgunj Medical Campus (MMC), Institute of Medicine (IOM), Tribhuvan University, Kathmandu, Bagmati, Nepal.
Junu Richhinbung RaiDepartment of Clinical Microbiology, Tribhuvan University Institute of Medicine Maharajgunj Medical Campus, Kathmandu, Bagmati, Nepal.ORCID 0000-0002-4737-2130
Laxman BharatiDepartment of Pharmacy, Maharajgunj Medical Campus (MMC), Institute of Medicine (IOM), Tribhuvan University, Kathmandu, Bagmati, Nepal.
Arjun BudthapaDepartment of Pharmacy, Maharajgunj Medical Campus (MMC), Institute of Medicine (IOM), Tribhuvan University, Kathmandu, Bagmati, Nepal.
Kul Prasad GhartiDepartment of Pharmacy, Maharajgunj Medical Campus (MMC), Institute of Medicine (IOM), Tribhuvan University, Kathmandu, Bagmati, Nepal.
Shiv Kumar SahDepartment of Pharmacy, Maharajgunj Medical Campus (MMC), Institute of Medicine (IOM), Tribhuvan University, Kathmandu, Bagmati, Nepal phrshiv@gmail.com.ORCID 0000-0002-8284-5925

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe sought to determine the prevalence and antimicrobial susceptibility pattern of methicillin-resistant

methodsCross-sectional, observational study design. STUDY

settingThe study was carried out at a tertiary care facility, the largest public hospital, Tribhuvan University Teaching Hospital (TUTH), Nepal.

participantsA total of 7433 clinical samples from hospital inpatients and outpatients available in the TUTH microbiology laboratory were examined. The study included clinical samples from the patients of either sex and across all age groups that had been clinically determined to have

resultsOf 7433 clinical samples analysed,

conclusionOur study indicated a high rate of MRSA and MDR-SA (Multidrug-resistant Staphylococcus aureus) prevalence in a Nepalese tertiary care hospital. Therefore, given the widespread burden of MRSA and the threat of the emergence of resistance to commonly used antibiotics, there is a need for the development, adoption and enforcement of appropriate control policies in these hospital settings. Regular surveillance, reporting mechanism as well as prudent use of antimicrobial agents are crucial to combating the progression of MDR-MRSA prevalence and antibiotic resistance.

Indexed as

Methicillin-Resistant Staphylococcus aureusStaphylococcal InfectionsAnti-Bacterial AgentsCross-Sectional StudiesDrug Resistance, MultipleHospitals, TeachingHumansMicrobial Sensitivity TestsNepalPrevalenceStaphylococcus aureusTertiary Health CareAnti-Bacterial AgentsBACTERIOLOGYEpidemiologyEPIDEMIOLOGYINFECTIOUS DISEASESPublic health

Identifiers

PMID37164471
PMCPMC10174000

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.