ArticleThe Journal of nutrition2023
Association between a Calcium-to-Magnesium Ratio and Osteoporosis among Puerto Rican Adults.
Article in The Journal of nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Article
- Buprestid Beetles of Togo: Ecological, Sociocultural, and Nutritional Impacts of a High Quality Food Source.Insects · 2026Article
- Dietary Magnesium and Calcium Intake in Relation to Metabolic Health Status in Iranian Adolescents with Overweight and Obesity.Current developments in nutrition · 2026Article
- Review
- Metal(oid) profiling of the common site of osteoporotic fractures with bone microarchitecture correlation analysis: a comparative study of hip fracture patients and healthy individuals.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025Article
- Review
- Bioactive Potential of BalkanMicroorganisms · 2025Article
- Minerals and Human Health: From Deficiency to Toxicity.Nutrients · 2025Review
- TNF receptor-associated factors: promising targets of natural products for the treatment of osteoporosis.Frontiers in physiology · 2025Review
- Editorial: Vitamin D and mineral ion homeostasis: endocrine dysregulation in chronic diseases.Frontiers in endocrinology · 2025Article
- The Role of Inflammatory and Nutritional Indices in Postmenopausal Osteoporosis: A Retrospective Study.Journal of clinical medicine · 2024Article
- Bone Health and Physical Activity - The Complex Mechanism.Aging and disease · 2024Review
- Osteoporosis: Causes, Mechanisms, Treatment and Prevention: Role of Dietary Compounds.Pharmaceuticals (Basel, Switzerland) · 2024Review
- The role of magnesium in the pathogenesis of osteoporosis.Frontiers in endocrinology · 2024Review
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6 authors.
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Abstract
backgroundThe ratio of calcium-to-magnesium intake (Ca:Mg) may be important for bone due to their competitive absorption. The Ca:Mg ratio has been related to health outcomes, but few studies have related it to bone.
objectivesThe purpose of this analysis was to examine associations between the Ca:Mg intake with bone mineral density (BMD) and osteoporosis among Puerto Rican adults.
methodsAdults, aged 47-79 y, from the Boston Puerto Rican Osteoporosis Study, with complete BMD and dietary data (n = 955) were included. BMD was assessed with dual-energy X-ray absorptiometry and diet by a food frequency questionnaire. Calcium and magnesium intakes from food were energy adjusted, and the Ca:Mg was calculated. Adjusted linear and logistic regression models were utilized for testing associations between Ca:Mg and bone outcomes.
resultsCalcium intake was greater in the highest compared with lowest tertile, whereas magnesium intake was similar across tertiles. Mean BMD at hip sites was higher in the middle, compared with the lowest, tertile. Higher odds of osteoporosis were observed for the highest and lowest tertiles, compared with the middle tertile, after adjustment (T3 compared with T2 OR: 2.79; 95% CI: 1.47, 5.3; T1 compared with T2 OR: 2.01; 95% CI: 1.03, 3.92). Repeated analyses without supplement users (n = 432) led to stronger differences and ORs, but lost significance for some comparisons.
conclusionsDietary calcium and magnesium are important for bone, perhaps not independently. The Ca:Mg intake ratio appeared most protective within a range of 2.2-3.2, suggesting that a balance of these nutrients may be considered in recommendations for osteoporosis..
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