Evidence map›Paper›PMID 37164117›Full record

ArticleFertility and sterility2023

A North American study of anthropometric factors and semen quality.

Marlon D Joseph, Elizabeth E Hatch, Martha R Koenig, Michael L Eisenberg, Tanran R Wang, Greg J Sommer, Sherri O Stuver, Kenneth J Rothman, Lauren A Wise

Abstract read
In one paragraph

Article in Fertility and sterility, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. The influence of lifestyle and biological factors on semen variability.Journal of assisted reproduction and genetics · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marlon D JosephDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts.
Elizabeth E HatchDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts.
Martha R KoenigDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts.
Michael L EisenbergDepartment of Obstetrics and Gynecology, Stanford University, Stanford, California; Department of Urology, Stanford University, Stanford, California.
Tanran R WangDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts.
Greg J SommerLabcorp, Burlington, North Carolina.
Sherri O StuverDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts.
Kenneth J RothmanDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts.
Lauren A WiseDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts. Electronic address: lwise@bu.edu.

Funding

An internet-based preconception cohort study in North America and DenmarkR01HD086742 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI LAUREN A WISE · 2016 to 2026
$6.7M
A prospective study of male factors, fertility, and pregnancy outcomesR01HD105863 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI EISENBERG, MICHAEL L, WISE, LAUREN A · 2021 to 2025
$3.6M
Feasibility of in-home semen testing in a North American preconception cohort studyR21HD094322 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI EISENBERG, MICHAEL L, WISE, LAUREN A · 2018 to 2019
$465k
Feasibility of an internet-based study of time-to-pregnancy in the United StatesR21HD072326 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI WISE, LAUREN A · 2013 to 2014
$337k
Lifestyle and psychosocial determinants of male subfertility: a prospective studyR03HD090315 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI WISE, LAUREN A · 2017 to 2018
$165k
NICHD NIH HHS R01 HD086742NICHD NIH HHS R01 HD105863NICHD NIH HHS R03 HD090315NICHD NIH HHS R21 HD072326NICHD NIH HHS R21 HD094322
6 · The paper itself

Abstract

objectiveTo evaluate the association between anthropometric measures and semen parameters.

designCross-sectional study. SUBJECTS: Male participants aged ≥21 years. We analyzed data from 659 males (1185 samples) participating in a semen testing substudy of the Pregnancy Online Study (PRESTO), a North American preconception cohort study. After enrollment, we invited males aged ≥21 years to perform at-home semen testing using the Trak system. EXPOSURE(S): Participants reported selected anthropometric variables (current weight, height, waist circumference, and weight at age 17 years) and covariate data via an online baseline questionnaire. MAIN OUTCOME MEASURE(S): We used generalized estimating equations models to estimate the percent difference in mean log-transformed semen parameter values and 95% confidence intervals (CI) for associations between selected anthropometric variables and semen volume (mL), sperm concentration (million/mL), and total sperm count (million), adjusting for sociodemographics, lifestyle factors, and medical history. We also evaluated World Health Organization-defined thresholds for low semen quality. RESULT(S): Percentage differences in mean log-transformed semen volume, sperm concentration, and total sperm count (95% CI) comparing current body mass index ≥35 vs. <25 kg/m CONCLUSION(S): Selected anthropometric factors were associated modestly with poorer semen quality.

Indexed as

SemenSemen AnalysisAdolescentAdultCohort StudiesCross-Sectional StudiesFemaleHumansMaleNorth AmericaPregnancySpermatozoaSperm CountSperm MotilityAnthropometrycohort studiesfecundityfertilitysemen quality

Identifiers

PMID37164117
PMCPMC10524695

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.