ReviewChemical reviews2023
Transition-Metal-Catalyzed C-H Bond Activation for the Formation of C-C Bonds in Complex Molecules.
Review in Chemical reviews, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.
What it found
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Who cites it
78 citing papers in PubMed.
- Flash Communication: Arene ηOrganometallics · 2026Article
- Design, Synthesis and Anticancer Evaluation of Novel SOMolecules (Basel, Switzerland) · 2026Article
- Deprotection of benzyl ethersGreen chemistry : an international journal and green chemistry resource : GC · 2026Article
- A Photoredox C-H Arene Functionalization toward Substituted Methyls.Journal of the American Chemical Society · 2026Article
- From Research to an Undergraduate Lab Bench: An Undergraduate-Level Guided-Inquiry Experiment to Explore a Cp*Ir(III)-CatalyzedJournal of chemical education · 2026Article
- Bis(pyridino-Inorganic chemistry · 2026Article
- Recent progress on Ni-catalysed alkyl-alkyl cross-coupling enabled by asymmetric hydrofunctionalization of alkenes.Chemical science · 2026Review
- Catalyst-Controlled Regiodivergent C-H Olefination of Furanyl Carbamates through a Rational Approach.JACS Au · 2026Article
- Exploring bacterial cytochrome P450s for selective activation of aliphatic C-H bonds in pentacyclic triterpenoids.Nature chemistry · 2026Article
- Solvent-temperature coupled hydride transfer controls product selectivity in the HSiRChemical science · 2026Article
- Alkali metal cation effects for rapid C-H activation by iron(0) complexes.Chemical science · 2026Article
- Carbonylative Synthesis of β-Trifluoromethylated Heterocyclic Ketones through 1,2-Trifluoromethylation and Minisci Carbonylation of Alkenes.Organic letters · 2026Article
- C-H Nitrooxylation: A Shortcut to Nitrate Esters.Topics in current chemistry (Cham) · 2026Review
- Algorithm-driven, phenotype-directed bioactive molecular discovery.Communications chemistry · 2026Article
- Rh(iii)-catalyzed oxidative C-H annulation of 6-arylpyridazin-3(2RSC advances · 2026Article
- Total Synthesis of Isoriccardin C and Isoriccardin D Based on a Hydroxyl-Directed Palladium-Catalyzed Intramolecular C-H Alkenylation.Organic letters · 2026Article
- Frontiers in manganese catalysis: a sustainable platform for bond construction and heterocycle synthesis.RSC advances · 2026Review
- Iron-Catalyzed Nucleophilic Substitution Reactions: An Overview.ACS omega · 2026Review
- Nickel-Catalyzed Intermolecular Cyclization of 2-Bromobenzamide: A General Strategy for Synthesizing 6(5H)-Phenanthridinone Derivatives.Molecules (Basel, Switzerland) · 2026Article
- Coordination-Induced Spin Modulation: Overcoming Spin Blocking in C-H Methylation with High-Spin Ferrous Complexes.ACS catalysis · 2026Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Site-predictable and chemoselective C-H bond functionalization reactions offer synthetically powerful strategies for the step-economic diversification of both feedstock and fine chemicals. Many transition-metal-catalyzed methods have emerged for the selective activation and functionalization of C-H bonds. However, challenges of regio- and chemoselectivity have emerged with application to highly complex molecules bearing significant functional group density and diversity. As molecular complexity increases within molecular structures the risks of catalyst intolerance and limited applicability grow with the number of functional groups and potentially Lewis basic heteroatoms. Given the abundance of C-H bonds within highly complex and already diversified molecules such as pharmaceuticals, natural products, and materials, design and selection of reaction conditions and tolerant catalysts has proved critical for successful direct functionalization. As such, innovations within transition-metal-catalyzed C-H bond functionalization for the direct formation of carbon-carbon bonds have been discovered and developed to overcome these challenges and limitations. This review highlights progress made for the direct metal-catalyzed C-C bond forming reactions including alkylation, methylation, arylation, and olefination of C-H bonds within complex targets.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.