ReviewAging and disease2023
Transcranial Magnetic Stimulation in Disorders of Consciousness: An Update and Perspectives.
Review in Aging and disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Repetitive transcranial magnetic stimulation targeting the dorsolateral prefrontal cortex promotes recovery of consciousness in patients with disorders of consciousness: a meta-analysis of randomized controlled trials.Journal of neurology · 2025Pooled it
- Repetitive Transcranial Magnetic Stimulation Combined With Median Nerve Electrical Stimulation for Severe Traumatic Brain Injury.Brain and behavior · 2026Trial
- Temporal interference stimulation for deep brain neuromodulation in humans.Nature biomedical engineering · 2026Review
- Ethical Considerations in Transcranial Focused Ultrasound Neuromodulation for Disorders of Consciousness.Neuromodulation : journal of the International Neuromodulation Society · 2026Article
- Non-invasive neuroregulation techniques applied to patients with consciousness disorders: a narrative review.Frontiers in human neuroscience · 2026Review
- State-dependent repetitive transcranial magnetic stimulation in disorders of consciousness.Frontiers in human neuroscience · 2026Review
- Mechanisms of arousal promotion and cortical plasticity induced by multi-target transcranial magnetic stimulation in patients with chronic disorders of consciousness.American journal of translational research · 2026Article
- Flickers of awareness: Cerebellar stimulation in disorders of consciousness.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Article
- The promise of transcranial focused ultrasound in disorders of consciousness: a narrative review.Critical care (London, England) · 2025Review
- rTMS combined with median nerve magnetic stimulation for prolonged disorders of consciousness following intracerebral hemorrhage: a randomized controlled trial protocol.Frontiers in neurology · 2025Article
- Utilizing Centromedian Thalamus Connectivity to Personalize Noninvasive Neuromodulation Targets.CNS neuroscience & therapeutics · 2024Article
- Association of total bilirubin and prognosis in disorders of consciousness.Scientific reports · 2024Article
- Article
- Magnetic Stimulation as a Therapeutic Approach for Brain Modulation and Repair: Underlying Molecular and Cellular Mechanisms.International journal of molecular sciences · 2023Review
- Research hotspots and frontiers of neuromodulation techniques in disorders of consciousness: a bibliometric analysis.Frontiers in neuroscience · 2023Article
- Current status and prospect of transcutaneous auricular vagus nerve stimulation for disorders of consciousness.Frontiers in neuroscience · 2023Review
- Impacts of repetitive transcranial magnetic stimulation parameters on cerebral hemodynamics in patients with disorders of consciousness.Frontiers in neurologyArticle
- Neuromodulation for pediatric disorders of consciousness: bridging the gap between adult evidence and developmental reality.Frontiers in neurologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Disorders of consciousness (DOC) is a state in which consciousness is affected by brain injuries, leading to dysfunction in vigilance, awareness, and behavior. DOC encompasses coma, vegetative state, and minimally conscious state based on neurobehavioral function. Currently, DOC is one of the most common neurological disorders with a rapidly increasing incidence worldwide. Therefore, DOC not only impacts the lives of individuals and their families but is also becoming a serious public health threat. Repetitive transcranial magnetic stimulation (rTMS) can stimulate electrical activity using a pulsed magnetic field in the brain, with great value in the treatment of chronic pain, neurological diseases, and mental illnesses. However, the clinical application of rTMS in patients with DOC is debatable. Herein, we report the recent main findings of the clinical therapeutics of rTMS for DOC, including its efficacy and possible mechanisms. In addition, we discuss the potential key parameters (timing, location, frequency, strength, and secession of rTMS applications) that affect the therapeutic efficiency of rTMS in patients with DOC. This review may help develop clinical guidelines for the therapeutic application of rTMS in DOC.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.